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Dhanesh Prajapati
Dr. Nishkruti Mehta
Dr. Pragnesh Patani


Nigella Sativa, Black Seeds, Medicinal Plant, Anti-hypertension, Anti-oxidant, Anti-Inflammatory, Thymoquinone


The medicinal herb Nigella sativa of the Ranunculaceae family is utilized extensively all over the world. It is widely used in several conventional medical systems, including Unani, Tibb, Ayurveda, and Siddha. Folklore has long used seeds and oil in a variety of food and medical systems. Numerous illnesses and disorders have been treated with Nigella sativa seeds in the past. The seed Nigella sativa, sometimes referred to as black caraway and "Kalonji," is well-known throughout the world. It is one of the most widely used medicinal plants in the world, and its fixed oil includes a variety of beneficial chemical compounds, including thymoquinone, thymohydroquinone, dithymoquinone, thymol, nigellicine, carvacrol, nigellimine, nigellicine, nigellidine, and alpha-hederin. Antioxidant, anti-inflammatory, antibacterial, antifungal, antiparasitic and antiprotozoal, antiviral, cytotoxic, anticancer, neuro-, gastro-, cardio-, hetapto-, and nephroprotective activities are just a few of the potential uses for Nigella sativa and its constituents, including some isolated compounds. This further reveals that the main bioactive component of the essential oil, thymoquinone, is responsible for the majority of the plant's medicinal capabilities. The pharmacological properties of Nigella sativa for the treatment of acne vulgaris, vitiligo, atopic dermatitis, plaque psoriasis, and wound healing are reviewed in this article based on the most recent research.

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