PERINATAL OUTCOME OF MECONIUM STAINED AMNIOTIC FLUID

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Dr Purva Mahapatra
Dr Subhalaxmi Dash
Dr Satyajit Jena
Dr Sudhanshu Sekhara Nanda
Dr Chintamani Mahanta

Keywords

meconeum stained amniotic fluid

Abstract

Objective To determine the perinatal outcome of labouring mothers with meconium-stained amniotic fluid (MSAF).


Methods A prospective observational  study was conducted among labouring mothers with meconiumstained amniotic fluid from  December  2019 to june 2020 at SCB Medical College ,Cuttack, Odisha, India . Data was collected with pretested structured questionnaires. A Chi-square test used to check statistical associations between variables. Those variables with a p-value of less than 0.05 were selected for cross-tabulation and binary logistic regression. P-value set at 0.05, and 95% CI was used to determine the significance of the association. Relative risk was used to determine the strength and direction of the association.


Result Among 556 participants, there where 278(50%) primigravida in a stained fluid group. Labour was induced in 145 (26.07%) of the stained fluid group and has a statistically significant association with meconium staining. The stained fluid group was twice more likely to undergo operative delivery compared with a non-stained fluid group. There were more low Apgar scores at birth (36.8% ), birth asphyxias (9% ), neonatal sepsis (1% ), neonatal death (1%), and increased admissions to neonatal intensive care unit among the meconium-stained group. Meconium aspiration syndrome was seen in 35(6.2%) of the stained fluid group.


Conclusion Meconium-stained amniotic fluid is associated with increased frequency of operative delivery, birth asphyxia, neonatal sepsis, and neonatal intensive care unit admissions compared to clear amniotic fluid.

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