STUDY OF HISTOLOGICAL FINDINGS AND MALIGNANCIES IN POSTMENOPAUSAL BLEEDING
Main Article Content
Keywords
Postmenopausal bleeding (PMB), Endometrial carcinoma, Histopathology.
Abstract
Background: Postmenopausal bleeding (PMB) accounts for about 10% of postmenopausal complaints. Being a symptom of varied etiologies and its strong association with malignancy, it should be diligently evaluated.
Aims: To evaluate the histopathological spectrum of lesions presenting as PMB. and to estimate the incidence of premalignant, and malignant lesions presenting as PMB and to confirm the benign nature of the lesions to prevent unnecessary radical treatment.
Setting: SCB Medical College, Cuttack, Odisha, India.
Materials and Methods: This prospective study done from January 2018 to December 2019 and included the endometrial biopsies/curettages and cervical biopsies sent for histopathological examination from clinically diagnosed cases of postmenopausal bleeding.
Results: Out of all the samples majority were benign lesions (44%), followed by premalignant (25%), malignant lesions (19%).
Conclusion: A variety of histopathological findings are seen in PMB. Benign pathologies were more common in our study but the collective proportion of premalignant and malignant lesions is considerably higher in this study. Accurate diagnosis makes it much easier to counsel the patient about further course of management, prevent unnecessary radical treatment for benign conditions, prompt treatment, and vigilant follow up for malignant lesions.
References
2. Bani-Irshaid 1 and A. Al-Sumadi Histological findings in women with postmenopausal bleeding: Jordanian figuresEastern Mediterranean Health Journal Vol. 17 No. 7, 2011.
3. Kothapally K, Bhashyakarla U. Postmenopausal bleeding: clinicopathologic study in a teaching hospital of Andhra Pradesh: IntJ Reprod Contracept Obstet Gynecol. 2013;2(3):344-48.
4. Ubeja A, Singh A. Clinicopathological evaluation of postmenopausal bleeding in rural hospital set up. Int J Reprod Contracept Obstet Gynecol 2017;6:3556-9.
5. Sonali Rathi, Sangeeta K, Manisha K. “Histopathological evaluation in women with Postmenopausal Bleeding and Associated Risk factors for Endometrial Carcinoma”. Journal of Evolution of Medical and Dental Sciences 2013; Vol2, Issue 24, June 17;Page:4397-4402.
6. Arati Mallick, Ritanjali Behera, Khetrabasi Subudhi. “Histopathological study of endometrium in postmenopausal bleeding”. Journal of Evolution of Medical and Dental Sciences 2013; Vol. 2, Issue 46, November 18; Page: 9010-9018.
7. Nirupama V, Suneetha Y, Prabha Devi K. PostMenopausal Bleeding: An Analytic Study of 100 Cases. International Journal of Science and Research. 2015:4:2319.
8. Muhammad Usman Tariq, Romana Idrees, Ahmed Raheem and Naila Kayani Spectrum of Histopathological Findings in Postmenopausal Bleeding Journal of the College of Physicians and Surgeons Pakistan 2015, Vol. 25 (11):794-797.
9. Rita D, Sunil Kumar KS, Rithesh SK. The clinicopathological study of postmenopausal bleeding. Int J Reprod Contracept Obstet Gynecol. 2016;5(11):3671- 3674.
10. Sharma DD, Chandnani KA. A study of aetiology and prevalence of malignancy in patients with postmenopausal bleeding. International Journal of Reproduction, Contraception, Obstetrics and Gynecology 2017;6:3973-8.
11. Gandi SR, Vishwekar PS. A study on correlation of Pap smear, colposcopy and colposcopic directed biopsy in women with unhealthy cervix. J. Evolution Med. Dent. Sci. 2017;6(7):515-518.
12. Yousaf S, Shaheen M. and Rana T. Frequency of Endometrial Carcinoma in Patients with Postmenopausal Bleeding. ANNALS 2010;16 290-94.
13. M. Pavani et al. Evaluation of histomorphological findings and malignancies in postmenopausal,Indian Journal of Pathology and Oncology, April-June, 2018;5(2):302-307
Article Sidebar
Article Details
This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.
All articles published in JPTCP are licensed under Copyright Creative Commons Attribution-NonCommercial 4.0 International License.
Dr Prayag Pratishriti Majhi
Senior Resident, Dept. of O&G, PRM Medical college, Baripada, Odisha, India (Ex PG, SCB Medical College, Cuttack)
Dr Subhalaxmi Dash
Asst Professor, Dept of O&G, MKCG Medical College, Berhampur, Odisha, India
Dr Satyajit Jena
Asst Professor, Dept of O&G, SCB Medical College, Cuttack, Odisha, India
Dr Sudhanshu Sekhara Nanda
Asst. Professor, Dept of O&G, PRM Medical College, Baripada, Odisha, India
Dr Chintamanai Mahanta
Asso. Professor, Dept. of O&G, PRM Medical College, Baripada, Odisha