Zinc Oxide Conjugated Rutin Trihydrate Nanocomposite For Application In Dry Socket

Main Article Content

S.Varshasree
Sandhya Sundar
Saranya Kannan
Ramya Ramadoss
Suganya Paneerselvam
Pratibha Ramani

Keywords

Alveolar osteitis,zinc oxide,rutin trihydrate,gel formulation,healing ,antimicrobial effect

Abstract

Background: Dry socket or Alveolar osteitis is one of the most common and unpleasant post operative conditions after the extraction of permanent tooth.Zinc oxide is used for the treatment of dry socket and it is considered to be effective in relieving pain.Rutin trihydrate is also effectively used for antimicrobial activity.
Aim: To formulate and assess the physical, biological and healing properties of Zinc oxide and rutin trihydrate nanocomposites (ZnO-RTn).
Materials And Methods: Nutrient broth (1.3grams) is taken as a culture medium and dissolved in 100ml of water and is sterilized at 120℃. The bone slab is washed in saline and UV exposure is given for 30 minutes.Streptococcus mutans is added.Zinc oxide conjugated rutin trihydrate is added in another beaker and is incubated for 24 hours.SEM analysis is carried out.
Result: The nanoparticle was found to be in triangular shape which gives better surface interaction. The other elements present in the material source are carbon, oxygen, zinc.The cell viability was found to be 76.32%.
Conclusion: Due to the improvised properties of the nanoparticles ,they can find applications in the treatment modalities of various diseases.

Abstract 116 | pdf Downloads 62

References

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42. Merchant, Aman, Subhabrata Maiti, Vaishnavi Rajaraman, Ashok Velayudhan, and Dhanraj M. Ganapathy. 2022. “Comparative Analysis of Pink and White Esthetics of Anterior Full Veneer Crown: Indian Scenario.” Journal of Advanced Pharmaceutical Technology & Research 13 (Suppl 1): S282–87.
43. Mouriaux, Frederic. 2022. “How to Analyze Conjunctival Inflammation in Dry Anophthalmic Socket Syndrome (DASS)?” Graefe’s Archive for Clinical and Experimental Ophthalmology = Albrecht von Graefes Archiv Fur Klinische Und Experimentelle Ophthalmologie, November. https://doi.org/10.1007/s00417-022-05899-w.
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45. Quercus Corporation. 1976. Assisting with Suture Placement, Removing Sutures and Treatment of Dry Sockets.
46. Rokohl, Alexander C., Katharina Wall, Marc Trester, Philomena A. Wawer Matos, Yongwei Guo, Werner Adler, Keith R. Pine, and Ludwig M. Heindl. 2022. “Novel Point-of-Care Biomarkers of the Dry Anophthalmic Socket Syndrome: Tear Film Osmolarity and Matrix Metalloproteinase 9 Immunoassay.” Graefe’s Archive for Clinical and Experimental
Ophthalmology = Albrecht von Graefes Archiv Fur Klinische Und Experimentelle Ophthalmologie, November. https://doi.org/10.1007/s00417-022-05895-0.
47. Sun, Yu-Qi, Rui Sun, and Ji-Hong Zhao. 2022. “The Efficacy of Minocycline Hydrochloride Ointment versus Iodoform Gauze for Alveolar Osteitis: A Prospective Cohort Study.” BMC Oral Health 22 (1): 448.
48. Thamizhanambi, Tamizh Paavai, Annasamy Rameshkumar, Ramadoss Ramya, Rajkumar Krishnan, Thayalan Dineshkumar, and Gunasekaran Nandhini. 2022. “Analysis of Metabolic Regulators PGC1-α and PGC1-β in Oral Squamous Cell Carcinoma with and without Hyperglycemia.” Asian Pacific Journal of Cancer Prevention: APJCP 23 (8): 2797–2803.
49. Thorat, Sagar D., and Kumar Nilesh. 2022. “Efficacy of Low-Level Laser Therapy in the Management of Postoperative Surgical Sequelae after Surgical Removal of Impacted Mandibular Third Molars.” National Journal of Maxillofacial Surgery 13 (Suppl 1): S52–56.
50. Yan, Yupeng, Xionghan Feng, Xiaoming Wang, Wei Li, Shuai Lan, Lirong Zheng, Qin Zhang, and Biao Wan. 2023. “Transformation of Zinc Oxide Nanoparticles in the Presence of Aluminum Oxide with Pre-Sorbed Phosphorus Ligands.” Environment International 173 (February): 107847.

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