Embryonic toxicology and antimicrobial potential of strontium nanoparticles synthesized using Oolong tea

Main Article Content

B.Sumedha
Sandhya Sundar
Rajesh kumar Shanmugam
Ramya Ramadoss
Suganya Paneerselvem
Pratibha Ramani

Keywords

oolong tea, strontium nanoparticles,zebrafish, Embryonic toxicity, antimicrobial potential

Abstract

Background: Oolong tea due to the presence of flavonoids such as catechins, theaflavins, and TheaSinensis is used as a reducing agent to prepare strontium nanoparticles. When developing metal nanoparticles, the plant extracts-mediated technique is very effective and advantageous compared to employing other techniques.
Aim: To synthesize and evaluate the cytotoxicity, embryonic toxicology and antimicrobial properties of strontium nanoparticles mediated through oolong tea.
Materials and methods: Oolong tea extract was prepared and added with Strontium oxide to synthesize the strontium nanoparticles. The embryonic toxicity of the prepared nanoparticles is determined by assessing the toxicity to the hatching rate and viability rate of zebrafish embryos in different concentrations . The antimicrobial potential of the produced nanoparticles were assessed by determining the zone of inhibition against the common oral pathogens such as staph.aureus, strep.mutans, E.faecalis, candida. Albicans.
Result: There was also concentration dependent alterations in the hatching and viability rate of zebrafish. The anti-microbial assessment demonstrated the mean zone of inhibition of 23mm against Enterococcus faecalis, 33mm against Staphylococcus aureus, 23mm against Streptococcus mutans and 9mm against Candida albicans, by the end of fourth day. Conclusion: Oolong tea shows strong antimicrobial activity when treated with strontium nanoparticles thus it can find a great application in preventive dentistry. 

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