Anti inflammatory activity of Aqueous extract of Garlic peel

Main Article Content

Joseph Linoj
Ramya Ramadoss
Suganya Panneer Selvam
Sandhya Sundar
Pratibha Ramani
Rajesh Kumar Shanmugam

Keywords

Anti inflammatory activity, Garlic peel, extract

Abstract

Introduction: Garlic (Allium sativum) is a species of bulbous flowering plant in the genus Allium. Its close relatives include the onion, shallot, leek, chive, Welsh onion, and chinese onion. It is native to central Asia and Northeastern Iran and has long been used as a seasoning worldwide, with a history of several thousand years of human consumption and use. It was known to ancient Eruptions and has been used as both a food flavoring and a traditional medicine. China produces 76% of the world's supply of garlic
Materials And Methods: The anti inflammatory activity for garlic peel was tested. 0.05 ml of aqueous extract of garlic peel was added to 0.45ml bovine serum albumin and pH of 6.3 utilizing a modest quantity of IN hydrochloric acid. These samples were incubated at room temperature for 20 min & heated at 55°C in water bath for 30 min. The sample were cooled and absorbance was estimated spectrophotometrically at 660nm. Diclofenac sodium was used as the standard.
Result: Aqueous extract of garlic peel have anti inflammatory activity
Conclusion: Aqueous extract of garlic peel have good anti inflammatory activity.Active ingredient is allicin which has antiinflammatory & antioxidative properties.

Abstract 286 | PDF Downloads 147

References

1. Amagase, Harunobu, Brenda L. Petesch, Hiromichi Matsuura, Shigeo Kasuga, and Yoichi Itakura. 2001. “Intake of Garlic and Its Bioactive Components.” The Journal of Nutrition. https://doi.org/10.1093/jn/131.3.955s.
2. Devi, N. Sanjana, Deepak Nallaswamy Veeraiyan, Vinay Sivaswamy, Subhabrata Maiti, Dhanraj M. Ganapathy, and Vaishnavi Rajaraman. 2022. “Phosphorescent Wax - The Novel Approach of Innovation.” Journal of Advanced Pharmaceutical Technology & Research 13 (Suppl 2): S496–99.
3. Eilat-Adar, Sigal, Tali Sinai, Chaim Yosefy, and Yaakov Henkin. 2013. “Nutritional Recommendations for Cardiovascular Disease Prevention.” Nutrients. https://doi.org/10.3390/nu5093646.
4. Eliopoulos, G. M., and C. B. Wennersten. 2002. “Antimicrobial Activity of Quinupristin-
Dalfopristin Combined with Other Antibiotics against Vancomycin-Resistant Enterococci.” Antimicrobial Agents and Chemotherapy. https://doi.org/10.1128/aac.46.5.1319-1324.2002.
5. Fridman, S., T. Sinai, and D. Zilberg. 2014. “Efficacy of Garlic Based Treatments against Monogenean Parasites Infecting the Guppy (Poecilia Reticulata (Peters)).” Veterinary Parasitology. https://doi.org/10.1016/j.vetpar.2014.02.002.
6. Ganapathy, Dhanraj, Chitra Shivalingam, Rajeshkumar Shanmugam, Ashok K. Sundramoorthy, Karthikeyan Murthykumar, Sivaperumal Pitchiah, Saravanan Sekaran, and Sathish Kumar Ramachandran. 2022. “Recent Breakthrough of Bismuth-Based Nanostructured Materials for Multimodal Theranostic Applications.” Journal of Nanomaterials 2022 (July). https://doi.org/10.1155/2022/4944320.
7. Helen, Reshma K., Parkavi Arumugam, and P. Sivaperumal. 2023. “Preparation of Crude Extract from Chaetomorpha Species Seaweed and Analysis of Their Antioxidant Property - An in Vitro Study.” Journal of Coastal Life Medicine 11 (January): 750–59.
8. Jonkers, Daisy, Judith Sluimer, and Ellen Stobberingh. 1999. “Effect of Garlic on Vancomycin-Resistant Enterococci.” Antimicrobial Agents and Chemotherapy. https://doi.org/10.1128/aac.43.12.3045.
9. Khatua, Tarak Nath, Ramu Adela, and Sanjay K. Banerjee. 2013. “Garlic and Cardioprotection: Insights into the Molecular Mechanisms.” Canadian Journal of Physiology and Pharmacology. https://doi.org/10.1139/cjpp-2012-0315.
10. Lawson, Larry D., and Christopher D. Gardner. 2005. “Composition, Stability, and Bioavailability of Garlic Products Used in a Clinical Trial.” Journal of Agricultural and Food Chemistry. https://doi.org/10.1021/jf050536+.
11. Mohanavel, V., S. Kannan, R. Mohan, K. Arul, A. H. Seikh, and A. Iqbal. 2023. “Impact of CNT Addition on Surface Roughness and Dimensional Characteristics of Polymer Nano-Composite Fabricated by FDM Method,” March. https://doi.org/10.21203/rs.3.rs-2637062/v1.
12. Palani, Harini, Lakshminarayanan Arivarasu, S. Rajeshkumar, and Lakshmi Thangavelu. 2021. “Anti-Cariogenic & Cytotoxic Activity of Red Sandal (Pterocarpus Santalinus) Ethanolic Extract.” Journal of Pharmaceutical Research International 33 (64B): 6.
13. Pranati, T., Roy Anitha, S. Rajeshkumar, and Thangavelu Lakshmi. 2019. “Preparation of Silver Nanoparticles Using Nutmeg Oleoresin and Its Antimicrobial Activity against Oral Pathogens.” Research Journal of Pharmacy and Technology. https://doi.org/10.5958/0974-360x.2019.00471.2.
14. Ramesh Kumar, K. R., K. K. Shanta Sundari, A. Venkatesan, and Shymalaa Chandrasekar. 2011. “Depth of Resin Penetration into Enamel with 3 Types of Enamel Conditioning Methods: A Confocal Microscopic Study.” American Journal of Orthodontics and Dentofacial Orthopedics: Official Publication of the American Association of Orthodontists, Its Constituent Societies, and the American Board of Orthodontics 140 (4): 479–85.
15. Sivam, Gowsala P. 2001. “Protection against Helicobacter Pylori and Other Bacterial Infections by Garlic.” The Journal of Nutrition. https://doi.org/10.1093/jn/131.3.1106s.
16. Sivam, Gowsala P., Johanna W. Lampe, Bruce Ulness, Susan R. Swanzy, and John D. Potter. 1997. “Helicobacter Pylori—in Vitrosusceptibility to garlic(Allium Sativum)extract.” Nutrition and Cancer. https://doi.org/10.1080/01635589709514512.
17. Thanish, Ahamed S., Arvina Rajasekar, and Mebin George Mathew. 2021. “Prevalence of Periodontal Disease among Individuals between 18-30 Years of Age: A Retrospective Study.” Annals of Medical and Health Sciences Research 0 (0). https://www.amhsr.org//abstract/prevalence-of-periodontal-disease-among-individuals-between-1830-years-of-age-a-retrospective-study-8496.html.
18. Uthrakumar, A., K. Vijayarani, K. Kumanan, and V. Thiagarajan. 2013. “Molecular Characterization of Thermostable Newcastle Disease Virus Isolated from Pigeon.” Indian Journal of Virology: An Official Organ of Indian Virological Society 24 (1): 42–47.
19. Vishnu Prasad, S., Madan Kumar, Mahesh Ramakrishnan, and Dhanalakshmi Ravikumar. 2018. “Report on Oral Health Status and Treatment Needs of 5-15 Years Old Children with Sensory Deficits in Chennai, India.” Special Care in Dentistry: Official Publication of the American Association of Hospital Dentists, the Academy of Dentistry for the Handicapped, and the American Society for Geriatric Dentistry 38 (1): 58–59.
20. Vivek Babu, B., Arvind Sivakumar, A. Sumathi Felicita, and Prasanna Arvind T.R. 2022. “Incidence Of Supernumerary Teeth In Uclp Patients Visiting Saveetha Dental College And Hospital.” Journal of Pharmaceutical Negative Results, October, 2702–6.

Most read articles by the same author(s)

1 2 3 > >>