Assessment of Anti-oxidant and Anti-inflammatory activity on aqueous solution of Acai berry extract

Shree Abiraami NS; Devika Pillai; S Rajeshkumar

doi:10.47750/jptcp.2023.30.15.030

Shree Abiraami NS

Saveetha dental college and hospital, Saveetha Institute and Medical and Technical science (SIMATS), Saveetha university, Chennai, India.

Devika Pillai

Senior lecturer, department of oral medicine and radiology, Saveetha dental college and hospital, Saveetha Institute and Medical and Technical science (SIMATS), Saveetha university, Chennai, India.

S Rajeshkumar

Professor, nano biomedicine lab, department of pharmacology, Saveetha dental college and hospitals, Saveetha Institute and Medical and Technical science (SIMATS), Saveetha university, Chennai, India.

Keywords

acai berry, anti-oxidant, anti-inflammatory, super fruit, Euterpe oleracea

Abstract

Aim: To evaluate the antioxidant and anti-inflammatory activity an aqueous solution of acai berry extract.
Methods: An invitro study of extracted aqueous solution of acai berry from 100 ml of distilled water with 1 gm of acai berry powder. After which aqueous solution is subjected to 5 different concentrations. To check anti-inflammatory and anti-oxidant activity DPPH assay and albumin denaturation assay were used.
Result: After 24 hours spectrophotometry reading of anti-inflammatory activity at 50 μl has 75% and anti-oxidant shows that 50 μl has 90 .3%.
Conclusion: We conclude that aqueous solution of acai berry proved to have good antioxidant and anti-inflammatory activity. In future this extract can be used as topical therapeutic herbal formulation in management of oral potentially malignant disorders.

Abstract 264 | PDF Downloads 185

References

1. Magalhães TSS de A, de Almeida Magalhães TSS, de Oliveira Macedo PC, Converti A, de Lima ÁAN. The Use of Euterpe oleracea Mart. As a New Perspective for Disease Treatment and Prevention [Internet]. Vol. 10, Biomolecules. 2020. p. 813. Available from: http://dx.doi.org/10.3390/biom10060813
2. Kim KJ, Kim Y, Jin SG, Kim JY. Acai berry extract as a regulator of intestinal inflammation pathways in a Caco‐2 and RAW 264.7 co‐culture model [Internet]. Vol. 45, Journal of Food Biochemistry. 2021. Available from: http://dx.doi.org/10.1111/jfbc.13848
3. Kang J, Xie C, Li Z, Nagarajan S, Schauss AG, Wu T, et al. Flavonoids from acai (Euterpe oleracea Mart.) pulp and their antioxidant and anti-inflammatory activities. Food Chem. 2011 Sep 1;128(1):152–7.
4. Baptista S de L, Copetti CLK, Cardoso AL, Di Pietro PF. Biological activities of açaí (Euterpe oleracea Mart.) and juçara (Euterpe edulis Mart.) intake in humans: an integrative review of clinical trials. Nutr Rev. 2021 Nov 10;79(12):1375–91.
5. Pirozzi AVA, Imbimbo P, D’Agostino A, Tirino V, Finamore R, Monti DM, et al. Antioxidant and Hypolipidemic Activity of Açai Fruit Makes It a Valuable Functional Food. Antioxidants (Basel) [Internet]. 2020 Dec 31;10(1). Available from: http://dx.doi.org/10.3390/antiox10010040
6. Schauss AG, Wu X, Prior RL, Ou B, Patel D, Huang D, et al. Phytochemical and nutrient composition of the freeze-dried amazonian palm berry, Euterpe oleraceae mart. (acai). J Agric Food Chem. 2006 Nov 1;54(22):8598–603.
7. ALNasser MN, Mellor IR, Carter WG. A Preliminary Assessment of the Nutraceutical Potential of Acai Berry ( sp.) as a Potential Natural Treatment for Alzheimer’s Disease. Molecules [Internet]. 2022 Jul 30;27(15). Available from: http://dx.doi.org/10.3390/molecules27154891
8. Moura RS de, Ferreira TS, Lopes AA, Pires KMP, Nesi RT, Resende AC, et al. Effects of Euterpe oleracea Mart. (AÇAÍ) extract in acute lung inflammation induced by cigarette smoke in the mouse. Phytomedicine. 2012 Feb 15;19(3-4):262–9.
9. Kang J, Thakali KM, Xie C, Kondo M, Tong Y, Ou B, et al. Bioactivities of açaí (Euterpe precatoria Mart.) fruit pulp, superior antioxidant and anti-inflammatory properties to Euterpe oleracea Mart [Internet]. Vol. 133, Food Chemistry. 2012. p. 671–7. Available from: http://dx.doi.org/10.1016/j.foodchem.2012.01.048
10. Chang SK, Alasalvar C, Shahidi F. Superfruits: Phytochemicals, antioxidant efficacies, and health effects - A comprehensive review. Crit Rev Food Sci Nutr. 2019;59(10):1580–604.
11. Silva AP de S, de Souza Silva AP, de Camargo AC, Lazarini JG, Franchin M, de Cassia Orlandi Sardi J, et al. Phenolic Profile and the Antioxidant, Anti-Inflammatory, and Antimicrobial Properties of Açaí (Euterpe oleracea) Meal: A Prospective Study [Internet]. Vol. 12, Foods. 2022. p. 86. Available from: http://dx.doi.org/10.3390/foods12010086
12. Wong DYS, Musgrave IF, Harvey BS, Smid SD. Açaí (Euterpe oleraceae Mart.) berry extract exerts neuroprotective effects against β-amyloid exposure in vitro. Neurosci Lett. 2013 Nov 27;556:221–6.
13. Yamaguchi KK de L, Pereira LFR, Lamarão CV, Lima ES, da Veiga-Junior VF. Amazon acai: chemistry and biological activities: a review. Food Chem. 2015 Jul 15;179:137–51.
14. Schauss AG, Ou B, Wu X. High radical oxygen scavenging (ROS) and antioxidant activity in Freeze‐dried Euterpe oleracea (OptiAcai) palm fruit pulp [Internet]. Vol. 20, The FASEB Journal. 2006. Available from: http://dx.doi.org/10.1096/fasebj.20.4.a145-c
15. Alessandra-Perini J, Rodrigues-Baptista KC, Machado DE, Nasciutti LE, Perini JA. Anticancer potential, molecular mechanisms and toxicity of Euterpe oleracea extract (açaí): A systematic review. PLoS One. 2018 Jul 2;13(7):e0200101.

PDF

Published

Jun 20, 2023

DOI https://doi.org/10.47750/jptcp.2023.30.15.030

How to Cite

Shree Abiraami NS, Devika Pillai, & S Rajeshkumar. (2023). Assessment of Anti-oxidant and Anti-inflammatory activity on aqueous solution of Acai berry extract. Journal of Population Therapeutics and Clinical Pharmacology, 30(15), 279–282. https://doi.org/10.47750/jptcp.2023.30.15.030