Antimicrobial activity, Cytotoxicity and Anti inflammatory activity of Papain and Bromelain based caries removal gel decorated with Silver Nanoparticles against oral microbes

Main Article Content

S B Divya
S.Delphine Priscilla Antony S
S Rajeshkumar

Keywords

Papain, Bromelain, cytotoxicity, antimicrobial,Tree species, Children

Abstract

Background: Traditionally caries removal has been always done using dental burs. There are other methods of caries removal as well. Chemico mechanical method of caries removal is one of the well known methods. This study is papain gel and bromelain gel which have been self prepared and used as caries removal agent.
Materials and methods: The cytotoxicity of the self prepared caries removal gel was tested by Brine Shrimp Lethality Assay. Antimicrobial activity was evaluated against S mutans, E faecalis, Lactobacillus and C albicans oral bacteria. Anti inflammatory activity was evaluated using albumin denaturation analysis.
Results: Self made caries removal gel is more effective against oral microbes S mutans, Lactobacillus and C albicans. Also it shows mora anti inflammatory and less cytotoxic effect than commercial caries removal gel.
Conclusion: Self made caries removal gel is more effective than commercially available gel.

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References

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