Antidiabetic activity of selenium nanoparticle synthesized using clove and cumin formulation
Main Article Content
Keywords
clove, cumin, anti diabetic, selenium synthesis, nanoparticles
Abstract
Background: Nanotechnology explores a lot of interesting approaches in the field of biomedicine. Researchers have recently developed interest in biomolecule mediated nanoparticle production because of its eco-friendly and non-toxic properties. Clova and cumin have long been used in traditional medicine to treat various illnesses.
Aim: The purpose of this study is to use clove and cumin extract to produce the selenium nanoparticles via green approach.
Materials And Method: Collection of clove and cumin extract then 1 g of clove and cumin, powder was dissolved in distilled water and boiled for 5–10 min at 60–70C. The solutions were then filtered using Whatman No. 1 filter paper. The filtered extract was collected, synthesis of selenium nanoparticles using an herbal formulation, and to finalise the anti- diabetic activity of silver nanoparticles.
Results: The antioxidant effect of selenium nanoparticles showed a higher percentage of inhibition at 50μg/ml in DPPH Assay and H2O2 Assay. The clove and cumin extract showed an increased percentage of inhibition with increasing concentration.
Conclusion: The clove and cumin formulation mediated selenium nanoparticles acts as potent antioxidant agents. It also has the least side effects compared to commercial drugs.
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