FREQUENCY OF OBESITY AMONG GASTROESOPHAGEAL REFLUX DISEASE PATIENTS
Main Article Content
Keywords
Frequency; Obesity; Gastro-esophageal Reflux Disease
Abstract
Background: Gastric reflux disease refers to uncomfortable symptoms or a consequence caused by reflux of stomach contents and has strong association with obesity.
Objective: The aim of the study was to find out the Frequency of Obesity among Gastro-esophageal Reflux Disease Patients
Methodology: The current correctional study was carried out at the Department of medicine, Bolan medical college/ Bolan medical complex hospital Quetta from January 2023 to June 2023 after taking permission from the ethical committee of the institute. 154 participants of both gender, aged 20 to 70, who had GERD symptoms for longer than the previous were enrolled in this study via non-probability sequential sampling throughout the previous four weeks. The obesity incidence in participants with gastroesophageal reflux disease was determined. SPSS version 20.0 was used for data analysis.
Results: Overall 154 participants took part in this study out of which male 97(62.98%) and females were 57(37.0%) Majority of the individuals were in the age group less than 40 years 89(57.7%) with followed by age group greater than 40 years 65(42.2%) with Mean height, weight and BMI 162.09 ± 9.56 cm, 71.92 ± 15.13 kg and28.55 ±6.02 correspondingly. Obesity was noted in 73(47.40) individuals with body mass index greater than 27.Majority of male participants were non obese while 61% of female had greater body mass index with noteworthy p value 0.018.
Conclusion: The current study concluded that gastro esophageal reflux disease has strong association with obesity. Obesity rate among individuals with gastro-esophageal reflux disease was observed in 47.3% study participants.
Objective: The aim of the study was to find out the Frequency of Obesity among Gastro-esophageal Reflux Disease Patients
Methodology: The current correctional study was carried out at the Department of medicine, Bolan medical college/ Bolan medical complex hospital Quetta from January 2023 to June 2023 after taking permission from the ethical committee of the institute. 154 participants of both gender, aged 20 to 70, who had GERD symptoms for longer than the previous were enrolled in this study via non-probability sequential sampling throughout the previous four weeks. The obesity incidence in participants with gastroesophageal reflux disease was determined. SPSS version 20.0 was used for data analysis.
Results: Overall 154 participants took part in this study out of which male 97(62.98%) and females were 57(37.0%) Majority of the individuals were in the age group less than 40 years 89(57.7%) with followed by age group greater than 40 years 65(42.2%) with Mean height, weight and BMI 162.09 ± 9.56 cm, 71.92 ± 15.13 kg and28.55 ±6.02 correspondingly. Obesity was noted in 73(47.40) individuals with body mass index greater than 27.Majority of male participants were non obese while 61% of female had greater body mass index with noteworthy p value 0.018.
Conclusion: The current study concluded that gastro esophageal reflux disease has strong association with obesity. Obesity rate among individuals with gastro-esophageal reflux disease was observed in 47.3% study participants.
References
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13. Lee YC, Yen AM, Tai JJ, Chang SH, Lin JT, Chiu HM, et al. The effect of metabolic risk factors on the natural course of gastro-oesophageal reflux disease. Gut 2009;58:174–181.
14. Tseng PH, Lee YC, Chiu HM, Huang SP, Liao WC, Chen CC, et al. Prevalence and clinical characteristics of Barrett's esophagus in a Chinese general population. J Clin Gastroenterol 2008;42:1074–9.
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16. Friedenberg FK, Rai J, Vanar V, Bongiorno C, Nelson D.B, Parepally M, et al. Prevalence and risk factors for gastroesophageal reflux disease in an impoverished minority population. Obes Res Clin Pract. 2010 Oct;4(4):261–69.
17. El-Serag HB, Ergun GA, Pandolfino J, Fitzgerald S, Tran T, Kramer JR. Obesity increases oesophageal acid exposure. Gut. 2007 Jun;56(6):749-55.
18. Park SK, Lee T, Yang HJ, Park JH, Sohn CI, Ryu S, et al. Weight loss and waist reduction is associated with mprovement in gastroesophageal disease reflux s ymptoms: a longitudinal study of 15295 subjects undergoing health checkups. NeurogastroenterolMotil. 2017 May;29(5).
19. Hsu WC, Araneta MR, Kanaya AM, Chiang JL, Fujimoto W. BMI cut points to identify at-risk Asian Americans for type 2 diabetes screening. Diabetes care. 2015 Jan 1;38(1):150-8.
20. Goh K. Changing epidemiology of gastroesophageal reflux disease in the Asian-Pacific region: An overview. J Gastroenterol Hepatol. 2004 Sep 1;19(s3).
21. Hampel H, Abraham NS, El-Serag HB. Meta-analysis: Obesity and the risk for GERD and its complications. Ann Intern Med. 2005 Aug 2;143(3):199-211
22. Crowell MD, Cheskin LJ, Musial F. Prevalence of gastrointestinal symptoms in obese and normal weight binge eaters. Am J Gastroenterol. 1994 Mar;89(3):387-91
23. Jacobson BC, Somers SC, Fuchs CS. Body-mass index and symptoms of gastroesophagel reflux in women. N Engl J Med. 2006 Jun 1;354(22):2340-8.
24. Locke GR 3rd, Talley NJ, Fett SL, Zinsmeister AR, Melton LJ 3rd.. Risk factors associated with symptoms of gastroesophageal reflux. Am J Med 1999; Jun;106(6):642-9
25. Iovino P, Angrisani L, Tremolaterra F, Nirchio E, Ciannella M, Borrelli V, et al. Abnormal esophageal acid exposure is common in morbidly obese patients and improves after a successful Lap-band system implantation. Surg Endosc2002; Nov 1;16(11):1631-5.
26. 26 O’Brien TF Jr. Lower esophageal sphincter pressure (LESP) and esophageal function in obese humans. J Clin Gastroenterol. 1980 Jun 1;2(2):145-8.
27. Hou XH, Xie XP, Xu H, Chen JDZ. Exaggerated gastric accommodation in patients with obesity. Gastroenterology 2004;126;A481:T13
28. Butt AK, Hashemy I. Risk factors and prescription patterns of gastroesophageal reflux disease: HEAL study in Pakistan. J Pak Med Assoc. 2014 Jul 1;64(7):751-7
2. Atkins D, Briss PA, Eccles M, Flottorp S, Guyatt GH, Harbour RT et al. Systems for grading the quality of evidence and the strength of recommendations II: pilot study of a new system. BMC Health Serv Res. 2005 Mar 23;5(1):25.
3. Vakil N, van Zanten SV, Kahrilas P Dent J, Jones R; Global Consensus Group. The Montreal definition and classification of gastroesophageal reflux disease: a global evidence-based consensus. Am J Gastroenterol 2006;101:1900-20.
4. Dent J, El-Serag HB, Wallander MA, Johansson S. Epidemiology of gastro-oesophageal reflux disease: a systematic review. Gut 2005;54:710-7.
5. Karim S, Jafri W, Faryal A, Majid S, Salih M, Jafri F, et al. Regular post dinner walk; can be a useful lifestyle modification for gastroesophageal reflux. J Pak Med Assoc. 2011 Jun;61(6):526-30.
6. Jafri N, Jafri W, Yakoob J, Islam M, Manzoor S, Jalil A, et al. Perception of gastroesophageal reflux disease in urban population in Pakistan. J Coll Physicians Surg Pak. 2005 Sep;15(9):532-4.
7. Zafar S, Haque IU, Tayyab GU, Rehman AU, Rehman AU, Chaudhry NU. Correlation of gastroesophageal reflux disease symptoms with body mass index. Saudi J Gastroenterol. 2008 Apr;14(2):53-7.
8. Sijabat H, Simadibrata M, Abdullah M, Syam AF. Gastroesophageal Reflux Disease in Obese Patients. Indones J Gastroenterol Hepatol Dig Endosc. 2008;9(1):10-15.
9. Corley DA, Kubo A. Body mass index and gastroesophageal reflux disease: a systematic review and meta-analysis. Am J Gastroenterol 2006;101:2619-28.
10. Hampel H, Abraham NS, El-Serag HB. Meta-analysis: obesity and the risk for gastroesophageal reflux disease and its complications. Ann Intern Med 2005;143:199-211.
11. Vaishnav B, Bamanikar A, Maske P, Reddy A, Dasgupta S. Gastroesophageal Reflux Disease and its Association with Body Mass Index: Clinical and Endoscopic Study. J Clin Diagn Res. 2017 Apr;11(4):OC01-OC04.
12. Nomura M, Tashiro N, Watanabe T, Hirata A, Abe I, Okabe T, et al. Association of symptoms of gastroesophageal reflux with metabolic syndrome parameters in patients with endocrine disease. ISRN Gastroenterol. 2014 Jan 30;2014:863206.
13. Lee YC, Yen AM, Tai JJ, Chang SH, Lin JT, Chiu HM, et al. The effect of metabolic risk factors on the natural course of gastro-oesophageal reflux disease. Gut 2009;58:174–181.
14. Tseng PH, Lee YC, Chiu HM, Huang SP, Liao WC, Chen CC, et al. Prevalence and clinical characteristics of Barrett's esophagus in a Chinese general population. J Clin Gastroenterol 2008;42:1074–9.
15. Nisar S, Piracha S, Masud F. The frequency of gastroesophageal reflux disease among obese. Pak J Med Health Sci Oct-Dec 2010;4(4):455-9.
16. Friedenberg FK, Rai J, Vanar V, Bongiorno C, Nelson D.B, Parepally M, et al. Prevalence and risk factors for gastroesophageal reflux disease in an impoverished minority population. Obes Res Clin Pract. 2010 Oct;4(4):261–69.
17. El-Serag HB, Ergun GA, Pandolfino J, Fitzgerald S, Tran T, Kramer JR. Obesity increases oesophageal acid exposure. Gut. 2007 Jun;56(6):749-55.
18. Park SK, Lee T, Yang HJ, Park JH, Sohn CI, Ryu S, et al. Weight loss and waist reduction is associated with mprovement in gastroesophageal disease reflux s ymptoms: a longitudinal study of 15295 subjects undergoing health checkups. NeurogastroenterolMotil. 2017 May;29(5).
19. Hsu WC, Araneta MR, Kanaya AM, Chiang JL, Fujimoto W. BMI cut points to identify at-risk Asian Americans for type 2 diabetes screening. Diabetes care. 2015 Jan 1;38(1):150-8.
20. Goh K. Changing epidemiology of gastroesophageal reflux disease in the Asian-Pacific region: An overview. J Gastroenterol Hepatol. 2004 Sep 1;19(s3).
21. Hampel H, Abraham NS, El-Serag HB. Meta-analysis: Obesity and the risk for GERD and its complications. Ann Intern Med. 2005 Aug 2;143(3):199-211
22. Crowell MD, Cheskin LJ, Musial F. Prevalence of gastrointestinal symptoms in obese and normal weight binge eaters. Am J Gastroenterol. 1994 Mar;89(3):387-91
23. Jacobson BC, Somers SC, Fuchs CS. Body-mass index and symptoms of gastroesophagel reflux in women. N Engl J Med. 2006 Jun 1;354(22):2340-8.
24. Locke GR 3rd, Talley NJ, Fett SL, Zinsmeister AR, Melton LJ 3rd.. Risk factors associated with symptoms of gastroesophageal reflux. Am J Med 1999; Jun;106(6):642-9
25. Iovino P, Angrisani L, Tremolaterra F, Nirchio E, Ciannella M, Borrelli V, et al. Abnormal esophageal acid exposure is common in morbidly obese patients and improves after a successful Lap-band system implantation. Surg Endosc2002; Nov 1;16(11):1631-5.
26. 26 O’Brien TF Jr. Lower esophageal sphincter pressure (LESP) and esophageal function in obese humans. J Clin Gastroenterol. 1980 Jun 1;2(2):145-8.
27. Hou XH, Xie XP, Xu H, Chen JDZ. Exaggerated gastric accommodation in patients with obesity. Gastroenterology 2004;126;A481:T13
28. Butt AK, Hashemy I. Risk factors and prescription patterns of gastroesophageal reflux disease: HEAL study in Pakistan. J Pak Med Assoc. 2014 Jul 1;64(7):751-7
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Published
Nov 17, 2023
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How to Cite
Tariq Mehmood, Samreen Bugti, Taqdees Zahra, & Tahira. (2023). FREQUENCY OF OBESITY AMONG GASTROESOPHAGEAL REFLUX DISEASE PATIENTS. Journal of Population Therapeutics and Clinical Pharmacology, 30(18), 3194-3199. https://doi.org/10.53555/x50css31
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Author Biographies
Tariq Mehmood
Medicine PGMI/sheikh Khalifa Bin Zayyed al nehan Hospital, Quetta
Samreen Bugti
Assistant professor, Department of Medicine, Bolan Medical College/ Bolan Medical Complex Hospital Quetta
Taqdees Zahra
Assistant Professor Medicine Department, Bolan Medical College/ Bolan Medical Complex Hospital, Quetta
Tahira
Assistant professor, Department of Medicine, Bolan Medical College/ Bolan Medical Complex Hospital, Quetta
How to Cite
Tariq Mehmood, Samreen Bugti, Taqdees Zahra, & Tahira. (2023). FREQUENCY OF OBESITY AMONG GASTROESOPHAGEAL REFLUX DISEASE PATIENTS. Journal of Population Therapeutics and Clinical Pharmacology, 30(18), 3194-3199. https://doi.org/10.53555/x50css31