NATURAL SUBSTANCES IN MODERN HEALTHCARE: AN EXPLORATION OF THE ROLE OF NATURAL SUBSTANCES, INCLUDING PHYTOTHERAPEUTICS AND HERBAL PRODUCTS, IN THE CONTEXT OF MODERN HEALTHCARE

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Sudhair Abbas Bangash
Hemraj Budhathoki
Sadia Sohail
Bander Alshehri
Urooj Ahmed Khan
Muhammad Nouman Majeed

Keywords

Medicinal plants, diabetes mellitus, hypertension, antidiabetic, antihypertensive.

Abstract

Background: Global adult population are affected by diabetes mellitus and arterial hypertension, which pose substantial cardiovascular risks. In  Pakistan, cardiovascular illnesses are the primary cause of morbidity and mortality. Arterial hypertension stands as a significant risk factor for coronary artery disease and stroke, ranking among the top ten causes of mortality worldwide. Diabetes mellitus is the leading cause of death in women, while ischemic heart disease prevails as the leading cause of death in men. 


Treatment Strategies: Various medicines  with diverse chemical compositions and modes of action are typically used to manage both disorders, aiming to normalize blood glucose and reduce blood pressure levels. However, the occurrence of side effects or hypersensitive reactions often necessitates the modification or discontinuation of therapy. 


Need for Innovation: Given these challenges, there is a critical need to develop novel medications with antidiabetic and antihypertensive effects, potentially utilizing medicinal plants as an alternative approach. Scientific interest in phytotherapeutics has facilitated research into medicinal plants and novel compounds with therapeutic capabilities. 


Research Focus: Studies supporting the use of medicinal plants or identifying novel compounds for these purposes have gained momentum. Notably,  Pakistan's rich tradition of traditional medicine has led to the identification of numerous plants with significant potential for treating diabetes mellitus and hypertension. These findings have garnered attention from various educational and research institutions. 


Conclusion: The exploration of medicinal plants as potential sources of antidiabetic and antihypertensive agents offers promising avenues for the development of effective therapies. Further research and collaboration between traditional knowledge and modern science hold the potential to unlock new treatment modalities for these prevalent and impactful health conditions. 

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