STAGE-SPECIFIC DRUG THERAPIES AND TREATMENT STRATEGIES FOR HEPATOCELLULAR CARCINOMA
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Abstract
Hepatocelluler cell cancer (HCC) is the top form of liver cancer & a key cause of death from cancer all over the world. What you can do to treat it rests much on how far it has gone, how the liver works, & how the sick one is doing. The Barcelona Clinic Liver Cancer (BCLC) list helps guide what to do in the clinic. Cures that can fix it, like cut out part of the liver, give a new liver, & small area burn are good for the start phase. For the mid phase, the go-to is TACE. For far-gone HCC, whole body drugs are key. Sorafenib was the first multi-use drug block to be okayed. It was top choice for a long time, though it has its limits due to not working after a bit & harm done. Since then, a lot more drugs like lenvatinib, regorafenib, cabozantinib, & ramucirumab have made more ways to treat. Also, drugs that block bad immune marks like nivolumab, pembrolizumab, & the mix of atezolizumab with bevacizumab have shown they help live longer for some. There are new study looks at mix of many drugs to block to fight the sickness in more ways & to do better overall. For the end stage HCC, the care aims to ease pain & help make life feel better. This text sums up the most recent ways to use drugs at each stage of HCC, shows the move from just one drug to many at once, & the hard tries still made to get the best out from treating it.
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