THE ROLE OF CORONARY BYPASS SURGERY IN REDUCING MORTALITY AND ENHANCING QUALITY OF LIFE AMONG HEART DISEASE PATIENTS

Main Article Content

Dr. Adel Moideen
Safiyyah Mukarram Khan
Anurang Rawat
Dr. Roohullah Amin Safi
Preeti Batheja
Indresh Yadav
Mohamad A. Khedari
Tawseef Ahmad

Keywords

mortality, surgery, bypass, graft, and coronary

Abstract

Background: Cardiovascular diseases are a predominant cause of mortality in industrialized nations, contributing to approximately 30% of deaths and imposing substantial economic burdens on healthcare systems. Coronary heart disease, a major contributor to cardiovascular mortality, necessitates effective management strategies to improve patient outcomes and quality of life.


Objective: This study aims to assess the role of coronary bypass grafting (CABG) in treating coronary heart disease, evaluating its success rates, complications, and the decision-making process involved in selecting appropriate graft types for individual cases.


Methods: We conducted a documentary bibliographic review focusing on the theoretical aspects of coronary bypass surgery. The data collection was primarily executed through electronic databases such as PubMed and Google Scholar, utilizing health sciences descriptors and MESH terms. The collected literature will undergo a thorough review to extract relevant information about the effectiveness and challenges of CABG.


Results: Preliminary findings underscore the crucial role of CABG in reducing mortality rates, extending patient longevity, and enhancing the quality of life for those suffering from coronary heart disease. Despite the complexity and risks associated with the surgical procedure, the success rate remains high. The choice of graft type, a critical component of the surgical strategy, varies based on individual patient conditions and has significant implications for outcomes.


Conclusion: Coronary bypass grafting stands as a pivotal intervention in cardiovascular medicine, especially for managing severe coronary heart disease. While the procedure is technically demanding and associated with various challenges, its high success rate and the significant improvement in patient outcomes justify its continued use as a treatment modality. Future research should focus on optimizing graft selection processes and minimizing surgical risks to enhance patient outcomes further.

Abstract 195 | Pdf Downloads 14

References

1. Ahmad, Y., Howard, J. P., Arnold, A. D., Cook, C. M., Prasad, M., Ali, Z. A., Parikh, M. A., Kosmidou, I., Francis, D. P., & Moses, J. W. (2020). Mortality after drug-eluting stents vs. coronary artery bypass grafting for left main coronary artery disease: a meta-analysis of randomized controlled trials. European Heart Journal, 41(34), 3228-3235.
2. Benedetto, U., Raja, S. G., Albanese, A., Amrani, M., Biondi-Zoccai, G., & Frati, G. (2015). Searching for the second best graft for coronary artery bypass surgery: a network meta-analysis of randomized controlled trials. European Journal of Cardio-Thoracic Surgery, 47(1), 59-65.
3. Deppe, A.-C., Arbash, W., Kuhn, E. W., Slottosch, I., Scherner, M., Liakopoulos, O. J., Choi, Y.-H., & Wahlers, T. (2016). Current evidence of coronary artery bypass grafting off-pump versus on-pump: a systematic review with meta-analysis of over 16 900 patients investigated in randomized controlled trials. European Journal of Cardio-Thoracic Surgery, 49(4), 1031-1041.
4. Dieberg, G., Smart, N. A., & King, N. (2016). On-vs. Off-pump coronary artery bypass grafting: a systematic review and meta-analysis. International Journal of Cardiology, 223, 201-211.
5. Favaloro, R. G. (1998). Landmarks in the development of coronary artery bypass surgery. Circulation, 98(5), 466-478.
6. Gaudino, M., Benedetto, U., Fremes, S., Ballman, K., Biondi-Zoccai, G., Sedrakyan, A., Nasso, G., Raman, J., Buxton, B., & Hayward, P. A. (2020). Association of radial artery graft vs saphenous vein graft with long-term cardiovascular outcomes among patients undergoing coronary artery bypass grafting: a systematic review and meta-analysis. Jama, 324(2), 179-187.
7. Gaudino, M., Samadashvili, Z., Hameed, I., Chikwe, J., Girardi, L. N., & Hannan, E. L. (2021). Differences in long-term outcomes after coronary artery bypass grafting using single vs multiple arterial grafts and the association with sex. JAMA cardiology, 6(4), 401-409.
8. McNichols, B., Spratt, J. R., George, J., Rizzi, S., Manning, E. W., & Park, K. (2021). Coronary artery bypass: review of surgical techniques and impact on long-term revascularization outcomes. Cardiology and Therapy, 10, 89-109.
9. Mullany, C. J. (2003). Coronary artery bypass surgery. Circulation, 107(3), e21-e22.
10. Saraiva, F. A., Leite-Moreira, J. P., Barros, A. S., Lourenco, A. P., Benedetto, U., & Leite-Moreira, A. F. (2020). Multiple versus single arterial grafting in coronary artery bypass grafting: A meta-analysis of randomized controlled trials and propensity score studies. International Journal of Cardiology, 320, 55-63.
11. Schmidt-RioValle, J., Abu Ejheisheh, M., Membrive-Jiménez, M. J., Suleiman-Martos, N., Albendín-García, L., Correa-Rodríguez, M., & Gómez-Urquiza, J. L. (2020). Quality of life after coronary artery bypass surgery: a systematic review and meta-analysis. International journal of environmental research and public health, 17(22), 8439.
12. Seshadri, N., Whitlow, P. L., Acharya, N., Houghtaling, P., Blackstone, E. H., & Ellis, S. G. (2002). Emergency coronary artery bypass surgery in the contemporary percutaneous coronary intervention era. Circulation, 106(18), 2346-2350.
13. Sipahi, I., Akay, M. H., Dagdelen, S., Blitz, A., & Alhan, C. (2014). Coronary artery bypass grafting vs percutaneous coronary intervention and long-term mortality and morbidity in multivessel disease: meta-analysis of randomized clinical trials of the arterial grafting and stenting era. JAMA Internal Medicine, 174(2), 223-230.
14. Solo, K., Lavi, S., Kabali, C., Levine, G. N., Kulik, A., John-Baptiste, A. A., Fremes, S. E., Martin, J., Eikelboom, J. W., & Ruel, M. (2019). Antithrombotic treatment after coronary artery bypass graft surgery: systematic review and network meta-analysis. BMJ, 367.
15. Velazquez, E. J., Lee, K. L., Deja, M. A., Jain, A., Sopko, G., Marchenko, A., Ali, I. S., Pohost, G., Gradinac, S., & Abraham, W. T. (2011). Coronary artery bypass surgery in patients with left ventricular dysfunction. New england journal of medicine, 364(17), 1607-1616.

Most read articles by the same author(s)