EXPLORING THE IMPACT OF DIALYSIS ON NEUROLOGICAL CONDITIONS: INSIGHTS FROM BIOCHEMICAL DATA IN CHRONIC KIDNEY DISEASE
Main Article Content
Keywords
Kidney Disease, Urea, Creatinine, Dialysis
Abstract
Background: Substances in the bodies of individuals undergoing dialysis during chronic kidney disease (CKD) exhibit notable changes. Creatinine and urea serve as markers of kidney function, with urea indicating kidney changes and creatinine reflecting glomerular filtration efficiency. Monitoring these markers is essential for managing individuals on dialysis.
Objective: This study aimed to investigate the neurological conditions of dialysis patients by analyzing biochemical data pre- and post-dialysis. A systematic review of literature, utilizing databases such as VHL, Google Scholar, SciELO, and recent publications from 2014 to 2023, was conducted to explore the relationship between biochemical variables, CKD, creatinine, urea, and dialysis.
Methods: A systematic search strategy was employed to identify relevant articles focusing on biochemical parameters and dialysis in individuals with CKD. Inclusion criteria encompassed studies examining changes in biochemical variables before and after dialysis. Data extraction and analysis were conducted to assess the impact of dialysis on neurological conditions in CKD patients.
Results: The systematic review revealed significant alterations in biochemical variables among individuals with persistent kidney disease, emphasizing the necessity for hemodialysis to restore metabolic values to normal levels. Creatinine and urea levels were particularly affected, indicating impaired kidney function. Monitoring these biochemical parameters is crucial for evaluating kidney function and guiding treatment decisions for dialysis patients.
Conclusion: Understanding the significance of biochemical indicators, such as creatinine and urea, is paramount for healthcare providers managing individuals with CKD undergoing dialysis. Regular monitoring of these markers allows for timely intervention and adjustments in treatment to optimize patient health and well-being. This systematic review underscores the importance of biochemical data in assessing neurological conditions and guiding therapeutic strategies for CKD patients on dialysis
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Dr. Adel Moideen
Senior Resident, Dr. D.Y Patil Medical College, Hospital and Research Centre, Pune, India Department of Nephrology
Sarosh Alam
PGY1 Internal, Department of Internal Medicine, Carepoint Health Bayonne Medical Center, US
Mohit Lakkimsetti
MBBS, Department of Internal Medicine, Mamata Medical College, Khammam, India
Imesha Kalansuriya
Medical Student, Medical University of the Americas, United States
Marcel Awasi
MD, Department of Internal Medicine, University of Arizona College of Medicine Phoenix, USA
Wahab Moustafa
SRH Waldklinikum Gera, Spine Surgery and Neurotrauma Unit, Germany
Mohamad Kinan Sultan
SRH Waldklinikum Gera, Spine Surgery and Neurotrauma Unit, Germany