Main Article Content

Tufail Ahmad
Rashid Ahmad
Zakir Ullah
Shahab Alam
Tooba wajid
Abrar Khan
Shahin shah khan


Hepatitis C, Hepatitis V, Type 2 Diabetes Mellitus


Hepatitis is the inflammation of the liver, it may be caused by one of several viruses but is often caused by exposure to certain chemicals, autoimmune diseases, or viral infection. For more than two decades, it has been considered that diabetes mellitus has been associated with chronic liver disease (HBV and HCV). To prove this hypothesis, our study was aimed to evaluate the association of Type 2 Diabetes Mellitus (Type 2DM) in patients suffering from Hepatitis B or C virus. Recognizing the susceptible age for the association of type 2DM with hepatitis and difference of gender was also evaluated.  The data of one year (March 2021-March 2022) of 330 patients (HBV and HCV) was taken from Khyber Teaching Hospital, Peshawar for survey. Among these 93 (28.18%) patients were HBV positive, whereas 237 (71.82%) were HCV positive, from the studied cases. Amongst the HBV patients, 18 (19.3%) were associated with type 2DM. However, in HCV patients, 54 (22.7%) were associated with type 2DM. Higher association of Hepatitis B with diabetes was found in male patients, whereas in case of association of type 2DM with Hepatitis C, the ratio of male and female patients was almost equal. Most of the patients (HBV and HCV) associated with type 2DM were above 40 years of age.

Abstract 39 | PDF Downloads 19


1. Ali M., Idrees M., Ali L., Hussain A., Rehman I., Saleem S and Afzal S., (2011). Hepatitis B virus in Pakistan: a systematic review of prevalence, risk factors, awareness status and genotypes.Virology Journal, 8(102); p. 1-9.
2. Allison M E D., Wreghitt T., Palmer C R and Alexander G J M., (1994). Evidence for a link between hepatitis C virus infection and diabetes mellitus in a cirrhotic population. Journal of Hepatology, 21(6); p. 1135-1139.

3. American Diabetes Association., (2009). Diagnosis and Classification of Diabetes Mellitus. Diabetes Care, 32(1); p. 62–67.
4. Antonelli A., Ferrari S M., Giuggioli D., Domenicantonio A D., Ruffilli I., Corrado A., Fabiani S., Marchi S., Ferri C., Ferrannini E and Fallahi P., (2014). Hepatitis C virus infection and type 1 and type 2 diabetes mellitus. World Journal of Diabetes, 5(5); p. 586-600.
5. Cardell K., (2009). Studies on Hepatitis B Vaccination and Factors Associated with the Vaccine Response. Linköping University Medical Dissertations, LiU-tryck, Linköping, Sweden.
6. Chen H F., Li C Y., Chen P., See T T and Lee H Y., (2006). Seroprevalence of Hepatitis B and C in Type 2 Diabetic patients. Journal China Medical Association, 69(4); p. 146-152.
7. Ephraim R K D., Nsiah P., Osakunor., D N M., Adoba P., Sakyi S A and Anto E O., (2014). Seroprevalence of Hepatitis B and C Viral Infections among Type 2 Diabetics: A Cross-sectional Study in the Cape Coast Metropolis. Annals of Medical and Health Sciences Research, 4(5); p. 719-722.
8. Franco E., Bagnato B., Marino M G., Meleleo C., Serino L and Zaratt L., (2012). Hepatitis B: Epidemiology and prevention in developing countries. World Journal Hepatology, 4(3); p. 74–80.
9. Hamid S., Umar M., Alam A., Siddiqui A., Qureshi H and Butt J., (2004). PSG consensus statement on management of hepatitis C virus infection. Journal Pakistan Medical Association, 54 (3); p. 54146–150.
13. Irshad M. K., Chaudhry A G and Ahmad A., (2014). Hepatitis prevalence among pregnant women of Wah cant. A case study of al-Moeed hospital. Science International Lahore, 26(1); p. 459-461.

Most read articles by the same author(s)