EFFECT OF DEPRESSION ON DIABETES CONTROL; A CROSS-SECTIONAL STUDY IN A TRUST HOSPITAL

Main Article Content

Kamran Ali
Ahmed Khayyam
Namra Tanvir
Muhammad Umair Raheem Awan
Zarian Khan
Fareeha Akram
Abdulla K. Alsubai
Sumaiya Asif Sayed
Hosam Alazazzi
Ibrahim Asim

Keywords

Depression, Diabetic control, Cross-Sectional Study, Trust Hospital, Comorbidity

Abstract

Background and Aim: Diabetes and dementia represent prevalent health conditions in our population, imposing a significant burden of disease on society. Despite the increasing prevalence of diabetes in Pakistan, there is no prominent study investigating the relationship between depression and diabetes. The objective of the current study was to see the effect of depression in the local population so that measures should be taken accordingly.


Patients and Methods: A cross-sectional was conducted on 70 patients in the department of Endocrinology, Bahria International Hospital, Lahore Pakistan from January 2023 to June 2023. Patient Health Questionnaire-9 (PHQ-9) and protocol was used for the assessment of depression severity.  Patients were grouped in five different categories for state of mind of the patients ranging from “no to minimal depression” to “severe depression”. HbA1C was checked at the same point of time as evidence of control of diabetes. Collected data was processed using SPSS.


Results: The optimal HbA1C control target is set at 7%. However, the mean HbA1C level in our population was 10.7%± 1.75%, indicating a significant improvement over the recommended 7%. Age-wise distribution of patients were as follows; 14 (20%) in 20-35 years, 27 (38.6%) in 36-50 years, and 29 (41.4%) had >50 years. There were 41 (58.6%) male and 29 (41.4%) female. The incidence of no depression, mild, moderate, and severe depression based on PHQ-9 was 30 (42.9%), 18 (25.7%), 14 (20%), and 8 (11.4%) respectively. There was no statistically significant difference in HbA1C between different groups of population. Similarly, there was no statistically significant effect of degree of depression on the control of diabetes. Frequency of severe depression in our population was also higher than general population, which may be due to either poor socio-economic status or poor diabetes control.


Conclusion: The present study observed that people presenting to the trust hospital have poor control of diabetes. There was no apparent effect of depression on glycemic control in this population, particularly among individuals with poorly controlled diabetes.

Abstract 190 | Pdf Downloads 84

References

1. Khan P, Qayyum N, Malik F, Khan T, Khan M, Tahir A: Incidence of anxiety and depression among patients with type 2 diabetes and the predicting factors. Cureus. 2019, 11:10.7759/cureus.4254
2. Saeedi, P.P.I., Salpea, P., Malanda, B., Karuranga, S., Unwin, N., Colagiuri, S., et al., Global and regional diabetes prevalence estimates for 2019 and projections for 2030 and 2045: Results from the International Diabetes Federation Diabetes Atlas, 9 th edition. Diabetes Res Clin Pract. 2019;157:107843.
3. Zuberi et al.: Association of depression with treatment outcomes in Type 2 Diabetes Mellitus:A cross-sectional study from Karachi, Pakistan. BMC Psychiatry 2011 11:27
4. Al Qusaibi B, Mosli H, Kattan W, et al. (June 16, 2022) Depression Among Patients With Type 2 Diabetes Mellitus at King Abdulaziz University Hospital (KAUH): A Cross-Sectional Study. Cureus 14(6): e25990. DOI 10.7759/cureus.25990.
5. Albarrak AI, Mohammed R, Assery B, Allam D, Al Morit S, Al Saleh R, Zare R: Evaluation of diabetes care management in primary clinics based on the guidelines of American Diabetes Association. Int J Health Sci.2018, 12:40-4.
6. Alzahrani A, Alghamdi A, Alqarni T, Alshareef R, Alzahrani A: Prevalence and predictors of depression, anxiety, and stress symptoms among patients with type II diabetes attending primary healthcare centers in the western region of Saudi Arabia: a cross-sectional study. Int J Ment Health Syst. 2019, 13: 10.1186/s13033-019-0307-6.
7. Rajput R, Gehlawat P, Gehlan D, Gupta R, Rajput M: Prevalence and predictors of depression and anxiety in patients of diabetes mellitus in a tertiary care center. Indian J Endocrinol Metab. 2016, 20: 10.4103/2230-8210.192924.
8. Zanoveli JM, de Morais H, Caroline da Silva Dias IC, Schreiber AK, de Souza CP, da Cunha JM: Depression associated with diabetes: from pathophysiology to treatment. Curr Diabetes Rev. 2016, 12:165-78. 10.2174/1573399811666150515125349.
9. Alzughbi T, Badedi M, Darraj H, Hummadi A, Jaddoh S, Solan Y, Sabai A: Diabetes-related distress and depression in Saudis with type 2 diabetes. Psychol Res Behav Manag. 2020, 13:453-8.10.2147/PRBM.S255631.
10. Salinero-Fort ,M.A. G.C.P., San Andrés-Rebollo, F.J., Cárdenas-Valladolid, J., Abánades-Herranz, J.C., Carrillo de Santa, P. .E, Chico-Moraleja, R.M., et al., Prevalence of depression in patients with type 2 diabetes mellitus in Spain (the DIADEMA Study) : results from the MADIABETES cohort. BMJ Open. 2018;8(9):e020768.
11. Anantha, E.V.M., G.S., Umadevi, R. Prevalence of depression in patients with type 2 diabetes mellitus and its association with fasting blood sugar levels, in an urban area of Kancheepuram district, Tamil Nadu. Int J Community Med Public Health. 2017;4:3399-3406.
12. Lunghi, C., Moisan, J., Grégoire, J.P., Guénette, L. Incidence of Depression and Associated Factors in Patients With Type 2 Diabetes in Quebec, Canada: A PopulationBased Cohort Study. Medicine (Baltimore). 2016;95(21):e3514.
13. Tamang, P. Study on the Prevalence of Depression and Anxiety among Diabetes Mellitus patients in Tertiary Care Hospital- A Prospective Cross-sectional Study. AJPCR. 2020;8(2):26-32.
14. Gebre, B.B., Anand, S., Assefa, Z.M. Depression and Its Predictors among Diabetes Mellitus Patients Attending Treatment in Hawassa University Comprehensive Specialized Hospital, Southern Ethiopia. J Diabet Res.2020;2020:7138513.
15. Farooqi, A., Khunti, K., Abner, S., Gillies, C., Morriss, R., Seidu, S. Comorbid depression and risk of cardiac events and cardiac mortality in people with diabetes: A systematic review and meta-analysis. Diabetes Res Clin Pract. 2019;156:107816.
16. Mendes, R., Martins, S., Fernandes, L. Adherence to Medication, Physical Activity and Diet in Older Adults With Diabetes: Its Association With Cognition, Anxiety and Depression. J clin med res. 2019;11(8):583-592.
17. Kroenke, K., Spitzer, R.L., Williams, J.B., Löwe, B. The Patient Health Questionnaire Somatic, Anxiety, and Depressive Symptom Scales: a systematic review. Gen Hosp Psychiatry. 2010;32(4):345-359.
18. Al-Mohaimeed AA: Prevalence and factors associated with anxiety and depression among type 2 diabetes in Qassim: a descriptive cross-sectional study. J Taibah Univ Med Sci. 2017, 12:430-6.10.1016/j.jtumed.2017.04.002
19. Mukrim ME, Alshammari NM, Alshammari WM, et al.: Prevalence of depression, anxiety, and stress among diabetes mellitus patients in Arar, Northern Saudi Arabia. Int J Med Dev Ctries. 2019, 3:229-33.10.24911/IJMDC.51-1542576396.
20. Sumlin LL, Garcia TJ, Brown SA, Winter MA, García AA, Brown A, Cuevas HE: Depression and adherence to lifestyle changes in type 2 diabetes: a systematic review. Diabetes Educ. 2014, 40:731-44.10.1177/0145721714538925.
21. B. Chireh, M. Li, and C. D'Arcy, “Diabetes increases the risk of depression: a systematic review, meta-analysis and estimates of population attributable fractions based on prospective studies,” Preventive Medicine Reports, vol. 14, p. 100822, 2019.
22. S. V. Bădescu, C. Tătaru, L. Kobylinska et al., “The association between diabetes mellitus and depression,” Journal of medicine and life, vol. 9, no. 2, pp. 120–125, 2016.
23. The Lancet Diabetes & Endocrinology, “Poor mental health in diabetes: still a neglected comorbidity,” The Lancet Diabetes and Endocrinology, vol. 3, p. 393, 2015.
24. K. Naicker, J. A. Johnson, J. C. Skogen et al., “Type 2 diabetes and comorbid symptoms of depression and anxiety: longitudinal associations with mortality risk,” Diabetes Care, vol. 40, no. 3, pp. 352–358, 2017.
25. K. Ganasegeran, P. Renganathan, R. A. Manaf, and S. A. R. AlDubai, “Factors associated with anxiety and depression among type 2 diabetes outpatients in Malaysia: a descriptive crosssectional single-centre study,” BMJ Open, vol. 4, no. 4, article e004794, 2014.
26. M. Udedi, A. S. Muula, R. C. Stewart, and B. W. Pence, “The validity of the patient health Questionnaire-9 to screen for depression in patients with type-2 diabetes mellitus in non-communicable diseases clinics in Malawi,” BMC Psychiatry, vol. 19, no. 1, p. 81, 2019.
27. A. S. Aminu, V. Chandrasekaran, and S. Nair, “Depression among patients with diabetes: a community-based study in South India,” Journal of Medical Sciences, vol. 37, no. 6, p. 237, 2017.
28. D. P. Pahari, R. Upadhyay, and C. K. Sharma, “Depression among diabetic patients visiting a diabetes center in Nepal,” Health Prospect, vol. 17, no. 1, pp. 21–25, 2018.
29. AlRuthia Y, Alwhaibi M, Almalag H, Almosabhi L, Almuhaya M, Sales I, Albassam AA, Alharbi FA, Mansy W, Bashatah AS, Asiri Y. The relationship between trust in primary healthcare providers among patients with diabetes and levels of depression and anxiety. PLoS One. 2020 Sep 11;15(9):e0239035.
30. Crispín‐Trebejo B, Robles‐Cuadros MC, Bernabé‐Ortiz A. Association between depression and glycemic control among type 2 diabetes patients in L ima, P eru. Asia‐Pacific Psychiatry. 2015 Dec;7(4):419-26.
31. Sharif H, Jan SS, Sharif S, Seemi T, Naeem H, Jawed Z. Depression and suicidal ideation among individuals with type-2 diabetes mellitus, a cross-sectional study from an urban slum area of Karachi, Pakistan. Frontiers in public health. 2023 Feb 23;11:1135964.

Most read articles by the same author(s)

1 2 > >>