INCIDENCE AND RISK FACTORS FOR SURGICAL RECURRENCE OF CROHN'S DISEASE FOLLOWING PRIMARY BOWEL RESECTION
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Keywords
Crohn’s disease, Risk factors, Incidence, surgical recurrence
Abstract
Aim: The aim of the current study was to determine the incidence and risk factors for surgical recurrence of Crohn’s disease following primary bowel resection.
Patients and Methods: A Prospective clinical study investigated 52 patients having Crohn’s disease (CD) in the General Surgery and Gastroenterology Department of Tertiary Care Hospitals of Pakistan from January 2022 to April 2024. Crohn’s disease patients with primary anastomosis and bowel resection were included. Detailed demographic data, clinical characteristics, preoperative parameters, disease duration, and different outcomes associated with anastomosis were recorded. SPSS version 26 was used for descriptive statistics.
Results: The overall mean age was 32.4±6.8 years. There were 34 (65.4%) male and 18 (34.6%) female. Based on location of disease, the incidence of ileum, colonic, ileocolonic, and upper gastrointestinal tract was 16 (30.8%), 4 (7.7%), 28 (53.8%), and 4 (7.7%), respectively. Ileojejuno, ileocolic, and colocolic were different location of anastomosis where 15 (29%), 32 (61%), and 5 (10%), respectively. Smoking and jejunoileal anastomosis contributed significantly in increased surgical recurrence risk. Contrarily, the surgical recurrence risk was reduced with laparoscopy, anastomotic stoma, and anastomosis.
Conclusion: The present study observed that jejunoileal anastomosis and smoking are the two significant risk factors that contributes to higher incidence of surgical recurrence following primary bowel resection.
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Faisal Masood
Medical Officer, Pir Abdul Qadir Shah Jeelani Institute of Medical Sciences, Gambat, Pakistan
Maryam Hidayat
General Surgeon, General Surgery, Northwest Hospital, Peshawar, Pakistan
Muhammad Husnain Ashiq
General Surgery Resident, Aziz Bhatti Shaheed Teaching Hospital, Gujrat, Pakistan
Talal Tariq
General Surgery Resident, Aziz Bhatti Shaheed Teaching Hospital, Gujrat, Pakistan
Muhammad Umair Raheem Awan
Department of Trauma and Surgery, DHQ Hospital, Mandi Bhauddin, Pakistan
Iffa Zafar
Medical Officer, Mohayudin Teaching Hospital, Mirpur, Azad Kashmir
Hosam Alazazzi
Royal College of Surgeons in Ireland, Bahrain
Kamel J. K. Walwil
Royal College of Surgeons in Ireland, Bahrain
Jumana Abdelrahman Diab
Royal College of Surgeons in Ireland, Bahrain