OPEN VS PERCUTANEOUS CORE NEEDLE BIOPSY (CNB) FOR MUSCULOSKELETAL MALIGNANCIES

Main Article Content

Qaisar Alam
Naeem Ullah
Muhammad Salman
Zulfiqar Ullah
Sajjad Haider

Keywords

musculoskeletal lesions, open biopsy, percutaneous core needle biopsy (CNB), diagnostic accuracy, healthcare costs, comparative analysis, musculoskeletal malignancies

Abstract

Background: Musculoskeletal lesions pose diagnostic challenges, requiring histopathologic verification for precise characterization. This study compares open biopsy and percutaneous core needle biopsy (CNB) for musculoskeletal malignancies.


Methods: The study was conducted at National Institute of Rehabilitation Medicine Islamabad during the period from January 2021 to July 2023. A retrospective analysis of medical records and diagnostic reports included patients undergoing either open biopsy or percutaneous CNB. Diagnostic accuracy, complication rates, hospitalization duration, and healthcare costs were assessed.


Results: Percutaneous CNB demonstrated superior diagnostic accuracy (46%) compared to open biopsy (42%), aligning with existing literature. Complication rates favored CNB (16%) over open biopsy (24%). CNB led to a significantly shorter hospitalization duration (1.5 days) compared to open biopsy (4 days). Cost analysis revealed a compelling advantage for CNB, with an average cost per case of PKR 825,000, contrasting with PKR 1,200,000 for open biopsy.


Conclusion: Percutaneous CNB emerges as a preferred option for musculoskeletal malignancy diagnosis, offering enhanced diagnostic accuracy, lower complication rates, shorter hospitalization, and cost-effectiveness. Economic considerations play a pivotal role in healthcare decision-making, emphasizing the need for a balanced approach considering both clinical and financial dimensions.

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