ASSESSMENT OF SPLENIC FUNCTION AMONG TRANSFUSION DEPENDENT THALASSEMIA PATIENTS
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Keywords
Thalassemia, Hypersplenism, Transfusion-Dependent Thalassemia, Splenectomy
Abstract
Transfusion-dependent thalassemia is a chronic disease that affects many individuals and has a significant impact on the healthcare system and society. This study sought to explore the prevalence and factors contributing to hypersplenism in transfusion-dependent thalassemia patients in the Khyber Pakhtunkhwa province of Pakistan. A single-center-based retrospective study was conducted on 50 randomly selected patients over a period of three months From February 2019 to April 2019 and data was analyzed using established statistical techniques. The results showed that all (n=50, 100%) of the participants developed hypersplenism at an average age of 6.86±1.9 years and underwent a splenectomy at an average age of 15.1±4.6 years. The study found that the average number of annual transfusions received by the patients was 19.1±7.7, with no significant change in transfusion frequency after splenectomy
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Muhammad Hamza
House Officer Northwest General Hospital and Research Centre, Peshawar
Salman Zahir
House Officer Northwest General Hospital and Research Centre, Peshawar
Aneela Khan
House Officer Northwest General Hospital and Research Centre, Peshawar
Sarwat Jahan
Associate Professor Pharmacology Northwest School of Medicine, Peshawar
Daniyal Ahmed
Final Year MBBS Northwest School of Medicine, Peshawar
Khansa Khan
Final Year MBBS Northwest School of Medicine, Peshawar