Assessment of stem cells growth characteristics ethyl gallate conjugated hydrogel

Main Article Content

Muskan Soni
Ramya Ramadoss
Raghunandakumar
P.Bargavi
Sandhya Sundar
Suganya Panneer Selvam
Pratibha Ramani

Keywords

stem cell, Gallic acid, ethyl gallate, scaffold

Abstract

Background: Stem cells are types of cells that can produce other cells which are able to develop into any kind of cells in the body. scaffolds are 3-D porous solid, that provides a spatial correct position of cell location .They hold enormous potential for tissue regeneration. Ethyl gallate exhibits non-toxic nature of cell line from different tissue origin ethyl Gallate also provides nutrition and has been proven.
Materials and methods: 20 ML of gelatin solution was taken and mixed or added with 20 MG of Gallic acid(ethyl Gallate). It is then poured into a dish (90 MM Patriplate). freezing it was done at 4°C for 12 hours in a 24L culture plate. Thin membrane is now fabricated and characterized by SEM and an anti-inflammatory test was also done.
Discussion: Gallic acid-based hydrogel was found to have a stimulatory effect on stem cell proliferation .Improved porosity of the hydrogel is also seen, to facilitate proliferation.
Conclusion: Gallic acid(Ethyl gallate) modified gelatin membranes seem to exhibit significant effect on stem cell growth, characteristics which can be effectively extrapolated to key regeneration strategies.

Abstract 113 | PDF Downloads 78

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