Histological comparison of three calcium silicate materials in the Pulpotomy of rat molars

Nikitha Suzanne Varghese; Karthik Ganesh Mohanraj; Ganesh Jeevanandan

doi:10.47750/jptcp.2023.30.10.002

Nikitha Suzanne Varghese

Post graduate, Pediatric and Preventive Dentistry, Saveetha Dental College and Hospitals, Saveetha Institute of Medical and Technical Sciences, Saveetha University, Chennai, India

Karthik Ganesh Mohanraj

Assistant Professor, Department of Anatomy, Scientist, Biomedical Research Unit and Laboratory Animal Center, Saveetha Dental College & Hospitals, Saveetha Institute of Medical And Technical Sciences (SIMATS), Saveetha University, Chennai - 600 077, Tamil Nadu, India.

Ganesh Jeevanandan

Reader, Pediatric and Preventive Dentistry, Saveetha Dental College and Hospitals, Saveetha Institute of Medical and Technical Sciences, Saveetha University, Chennai, India

Keywords

cost, calcium, molars, alternative

Abstract

Introduction: The importance of preservation of pulp tissue prolongs the vitality of the tooth. The introduction of calcium silicate cements has proven to increase the success rate of the treatment, but the increased cost of the material is a disadvantage. Thus the development of a new material which has a superior clinical effect and is safe and economical is of utmost importance.
Aim: The purpose of this research is to histologically evaluate a novel calcium silicate cement and correlate it to Biodentine and Mineral trioxide aggregate (MTA) as pulpotomy agents in a rat model.
Subjects and methods: A total of nine Wistar albino rats were divided into three groups equally. Pulpotomies were conducted on the caries free mandibular molars using the three calcium silicate cements- new calcium silicate cement, Biodentine, and MTA under general anaesthesia. Glass ionomer cement that had been resin-modified was used to seal access cavities. At 7, 14, and 28 days following surgery, pulpotomized teeth in both groups were examined histologically under a light microscope (10x).
Results: Over the course of the experimented time periods, the inflammatory cell response gradually decreased in all three groups.
Conclusions: The new calcium silicate cement has been shown to have a less inflammatory reaction. This new calcium silicate cement can be used as a cost-effective alternative pulpotomy agent in comparison to the commercially available cements.

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Published

May 13, 2023

DOI https://doi.org/10.47750/jptcp.2023.30.10.002

How to Cite

Nikitha Suzanne Varghese, Karthik Ganesh Mohanraj, & Ganesh Jeevanandan. (2023). Histological comparison of three calcium silicate materials in the Pulpotomy of rat molars. Journal of Population Therapeutics and Clinical Pharmacology, 30(10), 7–11. https://doi.org/10.47750/jptcp.2023.30.10.002