PREVALENCE OF ORAL MUCOSAL LESIONS AND ASSOCIATED SYSTEMIC CONDITIONS IN HOSPITALIZED PATIENTS: A CROSS-SECTIONAL STUDY

Main Article Content

Dr. Dinesh Solanki

Keywords

Oral mucosal lesions; Hospitalized patients; Systemic diseases; Prevalence; Cross-sectional study

Abstract

Oral mucosal lesions represent a significant health concern among hospitalized patients, often reflecting underlying systemic conditions. This study aimed to assess the prevalence of oral mucosal lesions and their association with systemic diseases among hospitalized patients at a tertiary care center in Maharashtra, India.


Methods: A hospital-based cross-sectional study was conducted at N. K. P. Salve Institute of Medical Sciences & Research Centre and Lata Mangeshkar Hospital, Maharashtra, from March 2016 to August 2016. A total of 600 hospitalized adult patients were examined using systematic sampling. Data were collected through structured interviews and clinical oral examinations following World Health Organization guidelines. Demographic information, medical history, and oral mucosal findings were recorded. Chi-square test and logistic regression were used for statistical analysis with significance set at p<0.05.


Results: The overall prevalence of oral mucosal lesions was 42.3% among hospitalized patients. The most common lesions included oral candidiasis (15.2%), ulcerative lesions (12.8%), coated tongue (10.5%), and oral lichen planus (5.3%). Male predominance was observed with a male-to-female ratio of 1.6:1. Diabetes mellitus (38.2%) and hypertension (32.5%) were the most prevalent systemic conditions. Significant associations were found between oral mucosal lesions and diabetes mellitus (p<0.001), hypertension (p=0.012), and duration of hospitalization exceeding seven days (p=0.008).


Conclusion: Hospitalized patients demonstrated high prevalence of oral mucosal lesions with strong associations to systemic conditions, particularly diabetes and hypertension. These findings emphasize the need for routine oral screening programs in hospital settings for early detection and comprehensive patient management.

Abstract 5 | Pdf Downloads 5

References

• Akintoye, S. O., & Greenberg, M. S. (2014). Recurrent aphthous stomatitis. Dental Clinics of North America, 58(2), 281-297. https://doi.org/10.1016/j.cden.2013.12.002
• Al-Maweri, S. A., Ismail, N. M., Ismail, A. R., & Al-Ghashm, A. (2013). Prevalence of oral mucosal lesions in patients with type 2 diabetes attending Hospital Universiti Sains Malaysia. Malaysian Journal of Medical Sciences, 20(2), 39-46.
• Babu, R. A., Chandrashekar, P., Kumar, K. K., Reddy, G. S., Chandra, K. L., & Rao, V. (2014). A study on oral mucosal lesions in 3500 patients with dermatological diseases in South India. Annals of Medical and Health Sciences Research, 4(Suppl 2), S84-S93. https://doi.org/10.4103/2141-9248.138019
• Berkovitz, B., Holl, G., & Moxham, B. (2015). Oral anatomy, histology and embryology (4th ed.). Mosby/Elsevier.
• Bhatnagar, P., Rai, S., Bhatnagar, G., Kaur, M., Goel, S., & Prabhat, M. (2013). Prevalence study of oral mucosal lesions, mucosal variants, and treatment required for patients reporting to a dental school in North India: In accordance with WHO guidelines. Journal of Family and Community Medicine, 20(1), 41-48. https://doi.org/10.4103/2230-8229.108183
• Chun, S. I., Su, W. P., & Lee, S. (1990). Histopathologic study of cutaneous lesions in Behçet's syndrome. Journal of Dermatology, 17(6), 333-341. https://doi.org/10.1111/j.1346-8138.1990.tb01653.x
• Feng, J., Zhou, Z., Shen, X., Wang, Y., Shi, L., Wang, Y., Hu, Y., Sun, H., & Liu, W. (2015). Prevalence and distribution of oral mucosal lesions: A cross-sectional study in Shanghai, China. Journal of Oral Pathology & Medicine, 44(7), 490-494. https://doi.org/10.1111/jop.12264
• García-Pola Vallejo, M. J., Martínez Díaz-Canel, A. I., García Martín, J. M., & González García, M. (2002). Risk factors for oral soft tissue lesions in an adult Spanish population. Community Dentistry and Oral Epidemiology, 30(4), 277-285. https://doi.org/10.1034/j.1600-0528.2002.00048.x
• Gonsalves, W. C., Chi, A. C., & Neville, B. W. (2007). Common oral lesions: Part I. Superficial mucosal lesions. American Family Physician, 75(4), 501-507.
• Kumar, G. S., & Bhaskar, S. N. (2015). Orban's oral histology and embryology (14th ed.). Elsevier.
• Kumar, S., Patel, R., Tadakamadla, J., Tibdewal, H., Duraiswamy, P., & Kulkarni, S. (2015). Prevalence and risk factors for oral potentially malignant disorders in Indian population. Advances in Preventive Medicine, 2015, Article ID 208519. https://doi.org/10.1155/2015/208519
• Lima, A. C., Falcão, A. E., Sales, R. A., Sales, M. P. U., & Melo, M. C. B. (2014). Prevalence of oral lesions in hospitalized patients with infectious diseases in Northern Brazil. The Scientific World Journal, 2014, 586075. https://doi.org/10.1155/2014/586075
• Majorana, A., Bardellini, E., Flocchini, P., Amadori, F., Conti, G., Campus, G., & Polimeni, A. (2010). Oral mucosal lesions in children from 0 to 12 years old. Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontology, 110(1), e13-e18. https://doi.org/10.1016/ j.tripleo.2010.02.025
• Mathew, A. L., Pai, K. M., Sholapurkar, A. A., & Vengal, M. (2008). The prevalence of oral mucosal lesions in patients visiting a dental school in Southern India. Indian Journal of Dental Research, 19(2), 99-103. https://doi.org/10.4103/0970-9290.40461
• Pedersen, A. M. L., Nauntofte, B., Smidt, D., & Torpet, L. A. (2015). Oral mucosal lesions in older people: Relation to salivary secretion, systemic diseases and medications. Oral Diseases, 21(6), 721-729. https://doi.org/10.1111/odi.12337
• Pentenero, M., Broccoletti, R., Carbone, M., Conrotto, D., & Gandolfo, S. (2008). The prevalence of oral mucosal lesions in adults from the Turin area. Oral Diseases, 14(4), 356-366. https://doi.org/10.1111/j.1601-0825.2007.01391.x
• Pocock, G., & Richards, C. D. (2013). Human physiology: The basis of medicine (4th ed.). Oxford University Press.
• Reichart, P. A. (2000). Oral mucosal lesions in a representative cross-sectional study of aging Germans. Community Dentistry and Oral Epidemiology, 28(5), 390-398. https://doi.org/10.1034/ j.1600-0528.2000.028005390.x
• Rivera-Hidalgo, F., Shulman, J. D., & Beach, M. M. (2004). The association of tobacco and other factors with recurrent aphthous stomatitis in an US adult population. Oral Diseases, 10(6), 335-345. https://doi.org/10.1111/j.1601-0825.2004.01049.x
• Roy, S., & Varshney, S. (2013). Oral dermatological conditions: A clinical study. Indian Journal of Otolaryngology and Head and Neck Surgery, 65(1), 97-101. https://doi.org/10.1007/s12070-011-0347-y
• Scully, C. (2013). Oral and maxillofacial medicine: The basis of diagnosis and treatment (3rd ed.). Churchill Livingstone Elsevier.
• Shulman, J. D., Beach, M. M., & Rivera-Hidalgo, F. (2004). The prevalence of oral mucosal lesions in U.S. adults: Data from the Third National Health and Nutrition Examination Survey, 1988-1994. Journal of the American Dental Association, 135(9), 1279-1286. https://doi.org/10.14219/jada.archive.2004.0403
• Silva, M. F. A., Barbosa, K. G. N., Pereira, J. V., Bento, P. M., Godoy, G. P., Gomes, D. Q. C., & França, V. T. (2015). Prevalence of oral mucosal lesions among patients with diabetes mellitus types 1 and 2. Anais Brasileiros de Dermatologia, 90(1), 49-53. https://doi.org/10. 1590/abd1806-4841.20153370
• Tavares, M., Lindefjeld Calabi, K. A., & San Martin, L. (2014). Systemic diseases and oral health. Dental Clinics of North America, 58(4), 797-814. https://doi.org/10.1016/ j.cden.2014.07.005
• Triantos, D. (2005). Intra-oral findings and general health conditions among institutionalized and non-institutionalized elderly in Greece. Journal of Oral Pathology & Medicine, 34(10), 577-582. https://doi.org/10.1111/j.1600-0714.2005.00356.x
• Villa, A., Stock, S., Aboalela, A., Nahle, F., Castellanos, A., & Woo, S. B. (2015). Oral medicine referrals at a hospital-based practice in the United States. Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, 119(4), 423-429. https://doi.org/10.1016/j.oooo.2015.01.003