COLLAPSING CARDIOVASCULAR AND RESPIRATORY PHYSIOLOGY: INCREASING TRENDS OF WHEAT PILLS (ALUMINUM PHOSPHIDE) POISONING IN RURAL NAWABSHAH, INTENSIVE CARE UNIT BASED OBSERVATIONS
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Keywords
Aluminum phosphide (Wheat Pills), Suicidal poisoning, accidental poisoning, Outcomes
Abstract
Study Objective: This study was aimed at determining the frequency and percentage of wheat pill poisoning with its clinical presentation and outcomes in our tertiary care ICU. Study Design and settings: It was an observational study conducted in ICU of the People’s University of medical and health sciences Nawabshah from June 2023 to December 2023. Material & Methods: Patients reported as the suicidal and accidental poisoning with wheat pills were admitted in the ICU and the treatment was provided according to emergency protocols. The required data was collected using the research proforma. Collected data was interpreted and results were generated using statistical package of social sciences 22. Result: We admitted 20 patients as the victims of wheat pill (aluminum phosphide) poisoning out of which 10 (50%) were males and 10(50%) were females with a male female ratio of 1:1 for involvement. There were 7(35%) cases which belonged to 30 years or below age group while 13(65%) cases belonged to the age group above 30 years. Only one patient survived while 19 patients couldn’t be saved with a mortality rate of 95%. Conclusion: Suicidal Wheat pill poisoning is becoming a common practice in the rural area of this region being an easily available and cheaper option whereas the accidental poisoning with this agent is very rare in this area.
References
2. Fayyaz AF. The relationship between rice tablet consumption and pathological signs leading to death: A study in Tehran. Ann Mil Health Sci Res 2015; 13:21-25.
3. Mehrpour O, Alfred S, Shadnia S, Keyler DE, Soltaninejad K, Chalaki N, et al. Hyperglycemia in acute aluminum phosphide poisoning as a potential prognostic factor. Hum Exp Toxicol 2008;27:591-595.
4. Mehrpour O, Jafarzadeh M, Abdollahi M. A systematic review of aluminium phosphide poisoning. Arh Hig Rada Toksikol 2012; 63:61-72.
5. Singh S, Bhalla A, Verma SK, Kaur A, Gill K. Cytochrome-c oxidase inhibition in 26 aluminum phosphide poisoned patients. Clin Toxicol (Phila) 2006; 44:155-158.
6. Chen F, Wen JP, Wang XP, Lin QM, Lin CJ. Epidemiology and characteristics of acute poisoning treated at an emergency center. World J Emerg Med. 2010; 1(2):154–6.
7. Chugh SN, Dushayant K, Ram S, Arora B. Incidence and outcome of aluminium phosphide poisoning in a hospital study. Indian J Med Res 2009; 94:232-35.
8. Sajjad Ali, Ishtiaq Ahmad, Ashraf, Zohra Islam4Syed Kashif Ali Shah, Nayab Ali.The effects of wheat pill poisoning (aluminum phosphide) dosage on arterial blood gases and their clinical outcome JPMA 2023;73(11) 2189-2195.
9. Bogle RG, Theron P, Brooks P, Dargan PI, Redhead J. Aluminium phosphide poisoning. Emerg Med J.2016; 23:33-35.
10. Chugh SN. Aluminium phosphide poisoning. J Indian Acad Med 2013; 4:83-89.
11. Singh D, Dewan I, Pandey AN, Tyagi S. Spectrum of unnatural fatalities in the Chandigarh zone of North East India: A 25 year autopsy study from a tertiary care hospital. J Clin Forensic Med. 2013; 10:145-52.
12. Chugh SN, Arora V, Sharma A, Chugh K. Free radical scavengers and lipid peroxides in acute aluminium phosphide poisoning. Indian J Med Res. 2011;104:190-93.
13. Iftikhar R, Tariq KM, Saeed F, Khan MB, Babar NF. Wheat Pill: Clinical characteristics and outcome. Pakistan Armed Forces Med J (PAFMJ). 2011; 61(3):486-7.
14. Khan AN, Khan R, Siddiqui N, Rana SP, Faqirullah, Masood R. Wheat Pill Poisoning: Management and outcome in cases reported in DG Khan District. Professional Med J 2021; 28(8):1096-1100.
15. Chugh SN. Aluminium phosphide poisoning. J Indian Acad Med 2013; 4:83-89
16. Khan MJ. Poisons implicated in homicidal, suicidal and accidental cases in NWFP. J Ayub Med Coll Abbottabad. 2016; 28(2):308–11.
17. Masoud RA, Barghash S. Laboratory prognostic potential for acute aluminum phosphide poisoning. Asian Acad Manag J 2013;11:213-238.
18. Ahuja H, Mathai AS, Pannu A, Arora R. Acute Poisonings Admitted to a Tertiary Level Intensive Care Unit in Northern India: Patient Profile and Outcomes. J Clin Diagn Res 2015;9:UC01-4.
19. Shahida S, Rahimi M, Pajomand A, Rasouli MH, Abdollahi M. Successful treatment of acute aluminium phosphide poisoning; possible benefit of coconut oil. Hum Exp Toxicol. 2015; 24:215-18.
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Muhammad Naeem
MBBS, DA, MS (Anaesthesiology), Assistant Professor, Department of Anaesthesiology, Surgical Intensive Care Unit and Pain Center, People’s University of Medical and Health for Women, Shaheed Benazir Abad, Sindh, Pakistan.
Muhammad Saleh Khaskheli
MBBS, FCPS (Anaesthesiology), Professor and HOD, Department of Anaesthesiology, Surgical Intensive Care Unit and Pain Center, People’s University of Medical and Health for Women, Shaheed Benazir Abad, Sindh, Pakistan.
Rafia Tabassusm
MBBS, FCPS (Anaesthesiology), Professor, Department of Anaesthesiology, Surgical Intensive Care Unit and Pain Center, People’s University of Medical and Health for Women, Shaheed Benazir Abad, Sindh, Pakistan.
Ashique Ali Arain
MBBS, MCPS (Family Medicine), M. Phil (Pharmacology), Consultant Family Physician and Associate Professor of Pharmacology, Liaquat Institute of Medical and Health Sciences, Thatta, Sindh Pakistan.
Aziz Ahmed Solangi
MBBS, M. Phil (Pharmacology) Lecturer Department of Pharmacology Bilawal Medical College, Jamshoro, Sindh, Pakistan.
Abdul Ghafoor
MBBS, M.Phil (Physiology) Assistant Professor, Department of Physiology Jhalawan Medical College Khuzdar, Baloachistan, Pakistan.