PROSPECTIVE STUDY ON IMPACT OF LIFESTYLE MODIFICATIONS ON BIOCHEMICAL PARAMETERS IN PATIENTS WITH CORONARY ARTERY DISEASE
Main Article Content
Keywords
coronary artery disease, lipid profile, hsCRP, uric acid and life style modifications
Abstract
Backdrop: Coronary artery disease (CAD) remains a leading cause of morbidity and mortality, with lifestyle factors playing a key role in disease progression and recurrence.
Objective: To evaluate the effect of structured lifestyle modifications on biochemical parameters in patients with established CAD.
Methods: A prospective interventional study was conducted involving CAD patients who underwent lifestyle changes over a 6-month period. Interventions included dietary adjustments, physical activity, and cessation of smoking and alcohol. Biochemical markers were assessed before and after the intervention.
Discussion: The majority of participants were aged 51–70 years, predominantly male, and urban dwellers. Post-intervention data revealed significant reductions in total cholesterol, LDL-C, VLDL, triglycerides, hs-CRP, uric acid, and fasting blood sugar, along with increased HDL-C levels. These changes reflect improved metabolic status, reduced inflammation, and lowered cardiovascular risk. Conclusion: Lifestyle modifications yielded substantial improvements in biochemical risk factors in CAD patients. Non-pharmacological interventions are vital for secondary prevention and long-term cardiovascular health enhancement.
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Amrapali Dasgupta
PhD Scholar, Dept. of Biochemistry, National Institute of Medical Sciences, Jaipur, Rajasthan
Dr. Sushma BJ
Professor and Head, Dept. of Biochemistry, National Institute of Medical Sciences, Jaipur, Rajasthan
Dr Amitesh Nagarwal
Associate Professor, Dept of Cardiology, National Institute of Medical Sciences, Jaipur, Rajasthan