PREVALENCE OF MASKED HYPERTENSION IN PATIENTS WITH METABOLIC SYNDROME COMPARED TO HEALTHY ADULTS- AN OBSERVATIONAL STUDY USING AMBULATORY BLOOD PRESSURE MONITORING
Main Article Content
Keywords
Metabolic Syndrome, Masked Hypertension, Nocturnal Variation, Blood Pressure (BP), Ambulatory Blood Pressure Monitoring (ABPM)
Abstract
Introduction: Metabolic syndrome is characterized by high clinic blood pressure (BP), abdominal obesity, impaired fasting glucose, low high-density lipoprotein (HDL) cholesterol, and high triglycerides. In some of these individuals, office BP measurement may be normal with underlying masked hypertension which require correct diagnosis and management to reduce cardiovascular event. Current study aims to assess prevalence of masked hypertension in this population.
Material and Methods: We have recruited 180 Study subjects allocated in two groups- Group A (90 patients with Metabolic Syndrome) and Group B (90 healthy controls without Metabolic Syndrome), who had normal office blood pressure measurement. Ambulatory blood pressure monitoring was done for all to assess 24hr average BP, night time average BP and day time average BP. Details of other cardiovascular risk factors and laboratory investigations were also collected.
Results: Prevalence of Masked Hypertension among group A or with Metabolic Syndrome (Cases) was 52.2%. Cases had more than twofold (2.42) higher risk of masked hypertension and were found statistically significant(p-value=0.0044). More subjects who consumed alcohol (37.78%) and smoke habits (56.67%) in cases Group A had increased levels of Clinic BP, waist circumference, fasting glucose levels and deranged lipid profile than Group B
Conclusion: Masked hypertension is present significant numbers in patients with metabolic syndrome compared to healthy controls. Correct diagnosis using ABPM and treatment with antihypertensive may further reduce risk of cardiovascular events.
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Dr Kritesh Mehta
DM Resident, Dept. of Cardiology, NIMS & R, Jaipur
Dr Amitesh Nagarwal
Assistant Professor, Dept. of Cardiology, NIMS & R, Jaipur
Dr Asharam Panda
Assistant Professor, Dept. of Cardiology, NIMS & R, Jaipur
Dr Sundeep Mishra
HOD Cardiology, NIMS & R, Jaipur