EXPLORING THE PHYTOCHEMICAL PROPERTIES OF SYZGIUM CUMINI PLANT EXTRACT AGAINST DIARRHOEA
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Keywords
Phytochemical Content, Essential Oil, Pharmaceutical Medications, Treatment of Diseases
Abstract
Syzgium cumini (jamun) has long been used to treat diabetes, gallstones, diarrhoea and other diseases. The majority of the positive effects of Syzgium cumini leaves are attributed to phytochemicals, present in leaves, including gallic acid, tannins, mallic acid, flavonoids, essential oils, jambolin, ellagic acid, jambosine, antimellin, and betulinic acid. Syzgium cumini has medicinal properties, including anticancer, antidiabetic, antifertility, anti-inflammatory, antidiarrheal, antimicrobial, antinociceptive, antioxidant, antiradiation, chemotherapeutic, and gastroprotective. The primary purpose of this article is to provide information about the phytochemical makeup and health benefits of jamun leaves. The phytochemical content and health-promoting properties of Syzgium cumini are identified by using the High-Performance Liquid Chromatography (HPLC) technique, suggesting that they could be employed as a component in the creation of pharmaceutical medications.
References
2. AH AJ, JF MAHDI, M FAROOQUI, and S YH. (2019). Gas Chromatography-mass spectroscopic analysis of black plum seed (Syzygium cumini) extract in hexane. GAS. 12(2).
3. Andleeb HA (2023).Comparative Study of Antibacterial, Antifungal, and Antioxidant activity of bitter apple Citrullus colocynthis plant parts in Methanol and n-Hexane. Tobacco Regulatory science (TRS) 1264-1279.
4. Boligon AA., and ML Athayde. (2014). Importance of HPLC in analysis of plants extracts. Austin Chromatogr. 1(3): 2.
5. Eshwarappa RSB, RS Iyer, SR Subbaramaiah, SA Richard, and BL Dhananjaya (2014). Antioxidant activity of Syzygium cumini leaf gall extracts. BioImpacts: BI: 4(2), 101.
6. Ilyas SI Ishfaq , DK Fatima, A Tariq, K Shahzadi, M Rashid, H Sohail, F Aslam, U Minhas, and T Arshid. (2024). Synergistic Effect of Zingiber Officinale (Ginger) and Curcuma Longa L. (Curcumin Analogs) for Anti-Inflammatory, Anti-Nociceptive Activity AND Analgesic Potentials. Journal of Population Therapeutics and Clinical Pharmacology. 31(3): 1363-1369.
7. Margaret E, AM Shailaja, and VV Rao. (2015). Evaluation of antioxidant activity in different parts of Syzygium cumini (Linn.). International Journal of Current Microbiology and Applied Sciences, 4(9): 372-379.
8. Minahil DM, H Sohail, H Tariq, M Jahangir, S Rehmat, M Akhtar, W Kiran, R Waseem, U Minhas, F Saleem. Preparation of Citrus Paradisi Vinegar from Varieties and Its Antioxidant And Nutritional Analysis. Journal of Survey in Fisheries Sciences. 10(1) 3305-3312.
9. Minhas U. (2023). Identification of Antibacterial and Antioxidant Activity of Syzigium Cumini Leaves Extracted Essential Oil Against Diarrhoea. Tobacco Regulatory Science (TRS). 1839-1847.
10. Mutha RE. AU Tatiya, and SJ Surana. (2021). Flavonoids as natural phenolic compounds and their role in therapeutics: An overview. Future journal of pharmaceutical sciences. 7: 1-13.
11. Sohail H. (2023). In Vitro Antibacterial Approach of Syzigium Cumini Leaves Extract against 13. Diarrhea Causing Bacteria by Using Different Biochemical Test. Tobacco Regulatory Science (TRS). 1526-1541.
12. Sonawane SK, SS Arya, and S Gaikwad (2013). Use of Jambhul powder in the development of bioactive components enriched milk kulfi. The Journal of Microbiology, Biotechnology and Food Sciences, 2(6): 2440.
13. Stankovic MS. (2011). Total phenolic content, flavonoid concentration and antioxidant activity of Marrubium peregrinum L. extracts. Kragujevac J Sci. 33(2011): 63-72.
14. Waseem R, A Asif, K Najam, U Minhas, R Asif, MM Arif, A Seerat, H Sohail, and M Akhtar (2023). Exploring Medicinal Plants Extracts For Antibacterial and Antiproliferative Properties: A Focus On Cannabis Sativa, Ficus Carica and Dodonea Viscosa. Journal of Population Therapeutics and Clinical Pharmacology. 30(17): 1497-1507.
15. Zhou W, Z Zhao, Z Yu, Z Hou, R Keerthiga, AND A Fu. (2022). Mitochondrial Transplantation therapy inhibits the proliferation of malignant hepatocellular carcinoma and its mechanism. Mitochondrion. 65: 11-22.
16. Ihara E, N Manabe, H Ohkubo, N Ogasawara, H Ogino, K Kakimoto and K Higuchi. (2024). Evidence-based clinical guidelines for chronic diarrhea 2023. Digestion. 105(6): 480-497.
17. Ahmed R, M Tariq, M Hussain, A Andleeb, MS Masoud, I Ali, and A Hasan. (2019). Phenolic contents-based assessment of therapeutic potential of Syzygium cumini leaves extract. PloS one. 14(8): e0221318.
18. Faria AF, MC Marques, and AZ Mercadante (2011). Identification of bioactive compounds from jambolão (Syzygium cumini) and antioxidant capacity evaluation in different pH conditions. Food chemistry. 126(4): 1571-1578.
19. Elansary HO, MZ Salem, NA Ashmawy, and MM Yacout, M. M. (2012). Chemical composition, antibacterial and antioxidant activities of leaves essential oils from Syzygium cumini L., Cupressus sempervirens L. and Lantana camara L. from Egypt. Journal of Agricultural science. 4(10): 144.
20. Atale N, A Jaiswal, A Chhabra, U Malhotra, S Kohli, S Mohanty, and V Rani. (2011). Phytochemical and antioxidant screening of Syzygium cumini seed extracts: a comparative study. J Pharm Res. 4(12): 4530-4532.
21. Gupta K, SP Singh, AK Manhar, D Saikia, ND Namsa, BK Konwar, and M Mandal, M. (2019). Inhibition of Staphylococcus aureus and Pseudomonas aeruginosa biofilm and virulence by active fraction of Syzygium cumini (L.) Skeels leaf extract: in-vitro and in silico studies. Indian journal of microbiology. 59: 13-21.
22. Kumawat M, J Damor, J Kachchhwaha, AK Garg, and C Singh, C. (2018). Pharmacological properties and therapeutic potential of Syzygium cumini (Jamun): A review. World Journal of Pharmaceutical Sciences. 7: 312-322.
23. Irfan M, O Polonskyi, A Hinz, C Mollea, F Bosco, T Strunskus, and M Ferraris. (2019). Antibacterial, highly hydrophobic and semitransparent Ag/plasma polymer nanocomposite coating on cotton fabric obtained by plasma based co-deposition. Cellulose. 26: 8877-8894.
24. Khare D. (2012). Pharmacognostical and Therapeutical Evaluation of Swietenia Mahagoni Jacq. Seeds and Jambu [Syzygium Cumini (Linn) Skeels.] Seeds in Madhumeha WSR to Diabetes Mellitus-a Comparative Study (Doctoral dissertation, Rajiv Gandhi University of Health Sciences (India)).
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Hajra Sohail
University of Central Punjab, Lahore,Pakistan
Maria Akhtar
The University of Lahore, Lahore, Pakistan
Sidra Shafique
Dr. Ikram-ul-Haq Institute of Industrial Biotechnology GC University, Government Collage University Lahore (GCU),Lahore,Pakistan
Seema Batool
Department of Development and Environmental Studies, Arctic Studies,Paris-Saclay University,Paris,France
Fatima Hamid
Research and Development Center, University of Health Sciences, Lahore,Pakistan
Raheela Sarwar
Center of Biotechnology and Microbiology, University of Peshawar,Peshawar,Pakistan
Ayesha Tabbasum
Department of Biological Sciences, Virtual University of Pakistan,Pakistan
Muhammad Tayab
Department of Zoology, University of Education, Lahore, Pakistan
Dr. Saman Zahra
Department of Biology, University of Okara, Okara, Pakistan
Dr. Farheen Aslam
Lahore College for Women University,Lahore,Pakistan
Usman Minhas
The University of Lahore, Lahore,Pakistan