SYNERGISTIC EFFECTS OF MORINGA OLEIFERA AND CARICA PAPAYA ON BLOOD GLUCOSE AND CHOLESTEROL LEVELS IN DIABETIC AND HYPERLIPIDEMIC RATS
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Keywords
Herbal therapy, antioxidants, fasting blood sugar, hyperlipidemia, Moringa oleifera, Carica papaya, and diabetes
Abstract
The therapeutic benefits of papaya leaf and Moringa oleifera on fasting blood sugar (FBS) and cholesterol levels in diabetic and hyperlipidemic mice were assessed in this study. The control group, Moringa oleifera-treated group, and Moringa oleifera + Papaya Leave-treated group comprised thirty adult male rats. Using conventional biochemical assays, FBS and cholesterol levels were assessed following a four-week course of therapy. Comparing the Moringa oleifera group (p=0.004) and the combination treatment group (p=0.001) to controls, the results showed a substantial decrease in FBS levels. Significant drops in cholesterol were also observed in both therapy groups (p=0.002 and p=0.001, respectively). Significant differences between the groups were confirmed by ANOVA. According to these results, papaya leaves and Moringa oleifera may be used in conjunction as complimentary treatments to treat hyperglycemia and hyperlipidemia. To confirm these results, more studies with bigger sample numbers and clinical trials are advised.
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Syed Muhammad Masood Ali
Department of pharmacology. Altibri Medical College Isra university .Karachi.
Syeda Afroz
Department of Pharmacology. Faculty of Pharmacy and Pharmaceutical Sciences. University of Karachi
Sayyada Humaira Masood
Department of physiology Altibri Medical College . Isra university Karachi.
Saeeda Naseer
Department of Pharmacology. Altamash institute of dental medicine. Clifton. karachi
Maryum Bano
Department of Pharmacology. Faculty of Pharmacy and Pharmaceutical Sciences. University of Karachi
Sheena Asghar
Department of Pharmacology. Faculty of Pharmacy and Pharmaceutical Sciences. University of Karachi