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Saba Munir
Yasir Nawaz
Fouzia Tanvir
Asma Umar
Aqeela Nawaz
Shumila Noreen
Hafiza Fizzah Riaz
Salman Ahmad
Huma Shaheen
Alia Iqbal


Cancer, Breast cancer, Clinical, Hematology, Pakistan


Introduction: Cancer is characterized by the uncontrolled proliferation of abnormal cells, capable of invading surrounding tissues. Breast cancer is very common in females, about 25%. The Complete Blood Count is a standard diagnostic assessment routinely ordered by physicians to assess various diseases.

Objectives: The purpose of this work was to investigate clinical characteristics with significant role of hematological parameters in breast cancer patients.

Materials and methods: Seventy cases were enrolled, with 15 subjects in the control group and an additional 25 women diagnosed with breast cancer serving as the case group. Hematological indices were studied by Sysmex KX-21N™automated analyzer tool.

Results: Among all patients, males comprised 3.33%, while females accounted for 96.67%.The mean and standard deviation of people with clinical details show age as 41.7± 6.67. All patients were diagnosed with Invasive Ductal Carcinoma. Various hematological parameters were examined. The mean and standard deviation of people for hematological indices among control was 3.45±4.22and breast cancer patients was 7.5±10.77. Hemoglobin, mean corpuscular volume, mean corpuscular hemoglobin, platelets count, and monocytes exhibited no statistical significance (p > 0.05), while others exhibited significance. The mean ± standard deviation of HCT, MCV, MCH, and MCHC among controls were 4.32 ± 5.25, 7.57 ± 9.28, 2.72 ± 3.33, and 0.89 ± 0.99, respectively. In contrast, among breast cancer patients, these values were 35.05 ± 5.92, 82.16 ± 9.02, 26.96 ± 3.58, and 32.6 ± 2.46, respectively.

Conclusion: In conclusion, a higher proportion of females were diagnosed with breast cancer, and all cases were identified as Invasive Ductal Carcinoma. Hematological profiles differed between the control and affected groups. Further studies are needed to thoroughly investigate hematological variations between these groups.

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