BIOACTIVE MOLECULES AND THERAPEUTIC POTENTIAL OF SOLANUM PSEUDOCAPSICUM FROM WESTERN HIMALAYAS, KASHMIR, PAKISTAN

Main Article Content

Muhammad Mohin Qureshi
Shakeel Sabir
Karamit Hussain
Taskeen Iqbal
Sajid Safeer
Muhammad Sohail
Mehreen Mushtaq
Ali Raza
Muhammad Shakeel Awan
Muhammad Shakil
Muhammad Sohail

Keywords

Anti-Fungal, Antioxidant, Pharmaceutical, Nutrition, DPPH

Abstract

Solanum pseudocapsicum L. commonly known as Jerusalem cherry or winter cherry belongs to the family Solanaceae. S. pseudocapsicum is an erect, branched, non-spiny, and bushy shrub. The Present research was conducted to analyze the bioactive molecules and therapeutic potential of the leaves and fruit of S. pseudocapsicum. The most important metabolites such as alkaloids, flavonoids, terpenoids, tannins, phlobatannins, steroids, cardiac glycosides, proteins, and carbohydrates from leaves and fruits were examined by qualitative tests. Antibacterial activity was carried out against Escherichia coli, Staphylococcus aureus, and Klebsiella pneumoniae, while antifungal activity was carried out against Aspergillus niger and Penicillium notatum using the disc diffusion method. The free radical scavenging ability was examined in extracts of methanol, ethanol, distilled water, and chloroform using the DPPH method. The calculated value of antioxidants was expressed as the IC50.The approximate analysis determined a reasonable amount of moisture, ash, crude fiber, crude fats, proteins, and carbohydrates. From this study, it is revealed that S. pseudocapsicum is highly enriched with nutrients and bioactive constituents and has vital therapeutic and antioxidant potential. Therefore, it can be used in the pharmaceutical and nutraceutical industries.

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