FREQUENCY OF ASYMPTOMATIC BACTERIURIA IN PREGNANT WOMEN

Main Article Content

Sadaf Abbas
Aisha Farukh
Khalida Salim
Saima Malik
Shahnaz Iqbal
Tayyaba Rashid

Keywords

Asymptomatic bacteriuria, Escherichia Coli, UTI, Urine Culture

Abstract

Background: Asymptomatic Bacteriuria (ABU) among pregnant women stands as a notable health concern that, regrettably, frequently escapes thorough scrutiny, demanding a meticulous exploration.


Objective: The objective of this research was to determine the frequency of Asymptomatic bacteriuria in pregnant women


Material and Methods: A Cross-Sectional Survey was carried out at the Department of Obstetrics & Gynecology, Jinnah Post Graduate Medical Centre in Karachi over a six-month period, from July, 2021, to January, 2022. A total of 241 pregnant women who met the inclusion criteria were included in the study. Randomly voided, clean-catch midstream urine samples (30–50ml) were collected in sterile wide-mouth containers (100ml) with covers for culture. Contamination was considered present if the urine culture revealed more than one type of organism. Subsequently, the urine culture was repeated after seven days.


Results: The average age of patients was 27.4 ± 7.3 years. Among the 241 women screened for asymptomatic bacteriuria, 17 (7.1%) tested positive, while 224 (92.9%) tested negative. Escherichia coli was identified as the most prevalent organism responsible for asymptomatic bacteriuria, present in 12 cases (70.5%).


Conclusion: Approximately 7.1% of pregnant women exhibit asymptomatic bacteriuria, with Escherichia Coli detected in 70.5% of cases. Routine urine culture for pregnant women is crucial to mitigate maternal and obstetric complications related to this condition during pregnancy.

Abstract 231 | pdf Downloads 67

References

1. Renko M, Tapanainen P, Tossavainen P, Pokka T, Uhari M. Meta-analysis of the significance of asymptomatic bacteriuria in diabetes. Diabetes care. 2011 Jan 1;34(1):230-5.
2. Silasi M, Cardenas I, Kwon JY, Racicot K, Aldo P, Mor G. Viral infections during pregnancy. American journal of reproductive immunology. 2015 Mar;73(3):199-213.
3. Manjula NG, Math GC, Patil A, Gaddad SM, Shivannavar CT. Incidence of urinary tract infections and its aetiological agents among pregnant women in Karnataka region. Advances in Microbiology. 2013 Oct 18;2013.
4. Parida B, ProjnaPaty B, Padhi A, Padhi S, Narasimham M, Sahu S. Prevalence of urinary tract infection in pregnant women in a Tertiary Care Hospital of Odisha. IOSR Journal of Dental and Medical Sciences. 2018;17(5):47-50.
5. Ali R, Afzal U, Kausar S. Asymptomatic bacteriuria among pregnant women. Annals of Punjab Medical College (APMC). 2011 Dec 12;5(2):155-8.
6. Kalinderi K, Delkos D, Kalinderis M, Athanasiadis A, Kalogiannidis I. Urinary tract infection during pregnancy: current concepts on a common multifaceted problem. Journal of Obstetrics and Gynaecology. 2018 May 19;38(4):448-53.
7. Rodríguez-Pardo D, Del Toro MD, Guío-Carrión L, Escudero-Sánchez R, Fernández-Sampedro M, García-Viejo MÁ, Velasco-Arribas M, Soldevila-Boixader L, Femenias M, Iribarren JA, Pulido-Garcia MD. Role of asymptomatic bacteriuria on early periprosthetic joint infection after hip hemiarthroplasty. BARIFER randomized clinical trial. European Journal of Clinical Microbiology & Infectious Diseases. 2021 Nov; 40:2411-9.
8. Vasudevan R. Urinary tract infection: an overview of the infection and the associated risk factors. J Microbiol Exp. 2014 May;1(2):00008.
9. Sirijatuphat R, Pongsuttiyakorn S, Supapueng O, Kiratisin P, Thamlikitkul V. Implementation of global antimicrobial resistance surveillance system (GLASS) in patients with bacteriuria. Journal of global antimicrobial resistance. 2020 Mar 1; 20:60-7.
10. Szweda H, Jóźwik M. Urinary tract infections during pregnancy-an updated overview. Dev Period Med. 2016 Jan 1;20(4):263-72.
11. Ahmed S, Shakooh S, Salati S, Muniem A. Prevalence of asymptomatic bacteriuria among pregnant women in Kashmir. Sri Lanka Journal of obstetrics and gynaecology. 2012 Oct 25;33(4).
12. Kalinderi K, Delkos D, Kalinderis M, Athanasiadis A, Kalogiannidis I. Urinary tract infection during pregnancy: current concepts on a common multifaceted problem. Journal of Obstetrics and Gynaecology. 2018 May 19;38(4):448-53.
13. Dash M, Sahu S, Mohanty I, Narasimham MV, Turuk J, Sahu R. Prevalence, risk factors and antimicrobial resistance of asymptomatic bacteriuria among antenatal women. Journal of Basic and Clinical Reproductive Sciences. 2013;2(2):92-6.
14. Ahmed S, Shakooh S, Salati S, Muniem A. Prevalence of asymptomatic bacteriuria among pregnant women in Kashmir. Sri Lanka Journal of obstetrics and gynaecology. 2012 Oct 25;33(4).
15. Awonuga DO, Dada-Adegbola HO, Fawole AO, Olola FA, Awonuga OM, Onimisi-Smith HO. Asymptomatic bacteriuria among an obstetric population in Ibadan. West African Journal of Medicine. 2011;30(2):89-93.
16. Ajayi AB, Nwabuisi C, Aboyeji AP, Ajayi NS, Fowotade A, Fakeye OO. Asymptomatic bacteriuria in antenatal patients in Ilorin, Nigeria. Oman medical journal. 2012 Jan;27(1):31.
17. Harini R. A Comparative study of single dose versus multi dose therapy for treatment of asymptomatic bacteriuria in pregnancy and study of prevalence and associated risk factors of asymptomatic bacteriuria in antenatal women in Kilpauk Medical College and Hospital (Doctoral dissertation, Kilpauk Medical College, Chennai).
18. Harini R. A Comparative study of single dose versus multi dose therapy for treatment of asymptomatic bacteriuria in pregnancy and study of prevalence and associated risk factors of asymptomatic bacteriuria in antenatal women in Kilpauk Medical College and Hospital (Doctoral dissertation, Kilpauk Medical College, Chennai).
19. Ali R, Afzal U, Kausar S. Asymptomatic bacteriuria among pregnant women. Annals of Punjab Medical College (APMC). 2011 Dec 12;5(2):155-8.
20. Turpin CA, Minkah B, Danso KA, Frimpong EH. Asymptomatic bacteriuria in pregnant women attending antenatal clinic at komfo anokye teaching hospital, kumasi, ghana. Ghana medical journal. 2007 Mar;41(1):26.
21. Ullah MA, Barman A, Siddique MA, Haque AK. Prevalence of asymptomatic bacteriuria and its consequences in pregnancy in a rural community of Bangladesh. Bangladesh Medical Research Council Bulletin. 2007;33(2):60-4.
22. Imade PE, Izekor PE, Eghafona NO, Enabulele OI, Ophori E. Asymptomatic bacteriuria among pregnant women. North American journal of medical sciences. 2010 Jun;2(6):263.
23. Fatima N, Ishrat S. Frequency and risk factors of asymptomatic bacteriuria during pregnancy. Journal of the College of Physicians and Surgeons--Pakistan: JCPSP. 2006 Apr 1;16(4):273-5.
24. Shankari P. Asymptomatic bacteriuria in pregnancy & its effect of screening & treatment on maternal and fetal outcome (Doctoral dissertation, Tirunelveli Medical College, Tirunelveli).