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Fahmida Gul
Samreen Memon
Ikramuddin Ujjan
Kanwal Abbas Bhatti
Pushpa Goswami
Waseemullah Shaikh


Physalis Peruviana, Breast Cancer, Tamoxifen resistance, Anxiety, Depression


Background: Physalis Peruviana has neuroprotective effects on anxiety and depression induced by Cancer. Psychosocial variables may influence breast cancer susceptibility and prognosis.

Objective: This research aims to evaluate the efficacy of Physalis Peruviana fruit extract in anxiety and depression due Breast cancer induced by DMBA in Albino rats.

Materials and Methods: The 60 female albino rats used in this study were divided into 05 groups and induced with tumor and treated for 10 weeks at Liaquat University of Medical and Health Sciences, Jamshoro.

Results: Rats in Group E demonstrated improving activity and reduction in depression and anxiety.

Conclusion: The Physalis Peruviana extract has neuroprotective effects on depression and anxiety.


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