INVESTIGATING PHARMACEUTICAL POTENTIAL OF GREEN TEA ON BIOCHEMICAL ALTERATIONS IN PLASMA AND BLOOD CAUSED BY CIGARETTE SMOKING

Abstract

Several harmful biochemical changes in plasma and blood are attributed to cigarette smoking, and these alterations are the target of treatment efforts. The current research looked at how regularly drinking green tea affects hard-core smokers. The blood of 120 healthy male volunteers was divided into four groups: nonsmokers, smokers, nonsmokers who also drank green tea, and smokers who also drank green tea. In addition to measuring glucose, HbA1c, hemoglobin, hematocrit, total cholesterol, lipoprotein patterns (HDL, LDL, VLDL), lipid peroxidation, vitamin D, vitamin B12, vitamin C, iron, total iron binding capacity, calcium, sodium, potassium, phosphorus, chloride, and aminotransferases (alanine aminotransferase, aspartate aminotransferase, gamma-glutamyl transfer (ALP) were used as biochemical markers. In addition, phenols, flavonoids, and tannins were found in green tea in a phytochemical study. Both 2, 2′-azino-bis (3-ethylbenzothiazoline-6-sulphonic acid) (ABTS+) and 2, 2-diphenyl-1-picrylhydrazyl (DPPH+) were used to measure the antioxidant and free radical scavenging capacities of green tea, respectively. The phytoconstituents in green tea were shown to be responsible for the reversal of the negative alterations seen in the aforementioned biochemical parameters in smokers, as shown by the results of this study. Green tea's phytocompounds have been shown to scavenge free radicals and protect against the smoking-induced metabolic changes in both in vivo and in vitro experiments.