A STUDY OF MEDICATION PATTERNS AND FACTORS INFLUENCING MEDICATION USE IN PREGNANCY AT A RURAL HEALTH BLOCK
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Keywords
Pregnancy, Prescriptions, Factors
Abstract
Background: Pregnancy is a transformative phase for a woman's body, involving numerous significant physiological adjustments. Safely managing various health conditions that may emerge during pregnancy is paramount to ensure the well-being of both the expectant mother and the developing fetus. Understanding these prescribing patterns is essential to provide better guidance to expectant mothers and healthcare providers alike, ensuring that any medication use during pregnancy is both necessary and safe.
Objective: To assess the patterns and factors affecting medication use along with prescription pattern during antenatal periods among pregnant women.
Methods: A cross-sectional study was conducted in a rural health block spanning from July 2022 to December 2022. After securing verbal consent from antenatal women, we gathered data on patient demographics, co-existent medical conditions, medications prescribed, and recording the details in a predefined format. Descriptive statistics was used to analyze the baseline data, chi-square test was used for categorical variables and multivariate logistic regression was used for factors influencing drug prescription.
Results: Among the 322 pregnant women who participated, 49% were primigravida; with a mean age of 27.6±3.1. Approximately 30% experienced at least one disease condition during pregnancy; with anemia (11%) being the commonest. The mean number of medications was 3.3 and 33.4% of participants received medication for a particular disease condition. Multivitamins/ minerals, antimicrobials and hormones were the commonest drug classes. Maternal age over 25 [(OR (CI): 1.26 (1.03–2.16) (p = .05)] and maternal illness [OR (CI) 2.03 (1.7–3.9) (p = .05)] were identified as factors affecting drug prescription.
Conclusion: Most of our patients were multigravida over the age of 25. Vitamins and minerals were the most commonly prescribed medications, with antimicrobials being the most frequently recommended drug class for specific disease conditions. Maternal age exceeding 25 years and maternal health status were identified as influential factors in drug prescription.
References
2. World Health Organization. WHO recommendations on antenatal care for a positive pregnancy experience. Geneva: WHO; 2016.
3. Mohseni M, Azami-Aghdash S, Gareh Sheyklo S, Moosavi A, Nakhaee M, Pournaghi-Azar F, Rezapour A. Prevalence and Reasons of Self-Medication in Pregnant Women: A Systematic Review and Meta-Analysis. Int J Community Based Nurs Midwifery. 2018 Oct;6(4):272–84.
4. Daw JR, Hanley GE, Greyson DL, Morgan SG. Prescription drug use during pregnancy in developed countries: a systematic review. Pharmacoepidemiol Drug Saf. 2011 Sep;20(9):895–902.
5. Mburu G, Ayon S, Mahinda S, Kaveh K. Determinants of Women’s Drug Use During Pregnancy: Perspectives from a Qualitative Study. Matern Child Health J. 2020 Sep;24(9):1170–78.
6. Andrade SE, Gurwitz JH, Davis RL, Chan KA, Finkelstein JA, Fortman K, et al. Prescription drug use in pregnancy. Am J Obstet Gynecol. 2004 Aug;191(2):398–407.
7. Pernia S, DeMaagd G. The New Pregnancy and Lactation Labeling Rule. P T. 2016 Nov;41(11):713–15.
8. Rajan B, Pasangha E, Devi P, George S. Patterns of Medication Use and Their Determinants in Pregnancy among Women Admitted to the Obstetrics Wards of a Tertiary Care Hospital: A Cross-Sectional Study. J Pharmacol Pharmacother. 2022;13(4):388–95.
9. Chaudhari A, Aasani D, Trivedi H. Drug utilization study in antenatal clinic of Obstetrics & Gynaecology. Indian J Pharm Pharmacol. 2016;3(4):186–91.
10. Asha B, Sunitha T. Prescription pattern during pregnancy in the tertiary care hospital of Kolar, India: A cross-sectional study. Indian J Obstet Gynecol Res. 2022;9(4):548–52.
11. Sharma R, Kapoor B, Verma U. Drug utilization pattern during pregnancy in North India. Indian J Med Sci. 2006;60(7):277–87.
12. Fikadu M, Kebebe D, Amelo W, Gashe F. Drug utilization pattern and potential teratogenicity risk among pregnant women visiting antenatal clinic: The case of a primary hospital. Indian J Pharm Pract. 2015;8(1):27–33.
13. Eze UI, Eferakeya AE, Oparah AC, Enato EF. Assessment of prescription profile of pregnant women visiting antenatal clinics. Pharmacy Practice. 2007;5(3):135–9.
14. Das B, Sarkar C, Datta A, Bohra S. A study of drug use during pregnancy in a teaching hospital in western Nepal. Pharmacoepidemiol Drug Saf. 2003;12(3):221–5.
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Dr. Saima Bashir
Department of Clinical Pharmacology, Sher-i-Kashmir Institute of Medical Sciences, Srinagar, Jammu and Kashmir, India
Dr. Sabah Nisar
Department of Pharmacology, Government Medical College, Srinagar, Jammu and Kashmir, India
Dr. Suhaib Qayoom
Clinical Research Unit, Department of Medicine, Carilion Clinic, Roanoke, Virginia, USA
Dr. Hibba Dar
Department of Pharmacology, Government Medical College, Srinagar, Jammu and Kashmir, India