EVALUATING MEDICATION COMPLIANCE IN INDIVIDUALS MANAGING TYPE II DIABETES MELLITUS
Main Article Content
Keywords
Adherence, Compliance, Awareness, Diabetes Mellitus
Abstract
Background: Type II Diabetes Mellitus (T2DM) is a chronic metabolic disorder that demands lifelong treatment and lifestyle modification. Despite the availability of effective pharmacological therapies, maintaining optimal glycaemic control remains a challenge for many patients due to poor adherence to prescribed medications. Non-compliance contributes significantly to disease progression, complications, and increased healthcare costs. Understanding the extent and reasons for medication non-adherence is therefore essential for improving patient outcomes and designing effective intervention strategies.
Aims & Objectives: This study is aimed at evaluating the medication compliance and adherence levels of patients with Type II Diabetes Mellitus.
Methods: A total of 183 participants, comprising 95 males and 88 females, diagnosed with Type 2 Diabetes Mellitus were provided the Morisky 8-item medication questionnaire to assess medication adherence, categorised as low, medium, or high. Additionally, awareness of the disease and reasons for compliance or non-compliance were evaluated. Categorical data was analysed using chi-square test.
Results: Among the participants, 68.4% of patients were aware of their prescribed medications, 81% were aware of the correct dosage and administration method, 87% were informed about the frequency of medication intake, 81% were aware of precautions, and 79% recognised the importance of medication compliance. However, 37 participants discontinued their prescribed medications, and 31 ceased treatment due to adverse effects. Medication adherence levels were categorised as high (12%), medium (29%), and low (59%), with significant differences (p<0.05). The most common reasons for non-adherence were forgetfulness (38%), high medication costs (28%), lack of awareness about the necessity (25%), and misconceptions (9%), with non-significant differences (p>0.05).
References
2. Sabaté E, editor. Adherence to Long-Term Therapies: Evidence for Action. Geneva: World Health Organization; 2003. 211 p.
3. World Health Organization. Adherence to long-term therapies: Evidence for action. Geneva: World Health Organization; 2003. Available from: https://www.who.int/chp/knowledge /publications/adherence_report/en/
4. Nau DP. Recommendations for improving adherence to Type 2 diabetes mellitus therapy—focus on optimizing oral and non-insulin therapies. American Journal of Managed Care. 2012;18(3 Suppl):S49–S54.
5. Clark M. Adherence to treatment in patients with Type 2 diabetes. Journal of Diabetes Nursing. 2004;8(10):386–390.
6. Garber MA, Nau DP, Erickson SR, Aikens JE, Lawrence JB. The concordance of self-report with other measures of medication adherence: A summary of the literature. Medical Care. 2004;42(7):649–652.DOI: 10.1097/01.mlr.0000129496.05898.02
7. Hasan A, Sharma V. Assessment of adherence to medication in patients with Type II diabetes mellitus. HECS International Journal of Community Health and Medical Research. 2018;4(4):74–76.DOI: 10.21276/ijchmr
8. Paes AHP, Bakker A, Soe-Agnie CJ. Impact of dosage frequency on patient compliance. Diabetes Care. 1997;20(10):1512–1517.DOI: 10.2337/diacare.20.10.1512
9. Aikens JE, Piette JD. Longitudinal analysis of medication adherence among adults with diabetes. Diabetes Care. 2009;32(8):1324–1329.DOI: 10.2337/dc08-2112
10. Rwegerera GM. Adherence to anti-diabetic drugs among patients with Type 2 diabetes mellitus at Muhimbili National Hospital, Dar es Salaam, Tanzania: A cross-sectional study. Pan African Medical Journal. 2014;17:252. DOI: 10.11604/pamj.2014.17.252.3262
11. Raj R, Majumdar A, Panda S, Chatterjee S, Ghosh A, Bhattacharya B. Medication non-adherence and poor glycaemic control in Indian Type 2 diabetes patients. Indian Journal of Endocrinology and Metabolism. 2016;20(5):658–664. DOI: 10.4103/2230-8210.190558
12. Ayele AA, Tegegn HG. Predictors of medication adherence among patients with Type 2 diabetes mellitus at the University of Gondar Referral Hospital, Northwest Ethiopia. BMC Public Health. 2019;19(1):1–10. DOI: 10.1186/s12889-019-6498-7
13. Khunti K, Gomes MB, Pocock S, Shestakova MV, Pintat S, Fenici P, et al. Therapeutic inertia in the treatment of hyperglycaemia in patients with Type 2 diabetes: A systematic review. Diabetic Medicine. 2021;38(2):e14404.DOI: 10.1111/dme.14404
