ASSESSMENT OF CHANGE IN MACULAR THICKNESS USING OPTICAL COHERENCE TOMOGRAPHY AFTER UNEVENTFUL PHACOEMULSIFICATION
Main Article Content
Keywords
Macular oedema, macular thickness, optical coherence tomography
Abstract
Background: Macular oedema, including cystoid macular oedema, is one of the primary causes of unfavourable visual outcomes after cataract surgery.
Objectives: To determine the frequency of macular oedema after uncomplicated phacoemulsification.
Methodology: It was a descriptive case series study. The study was conducted at the Department of Ophthalmology, Services Hospital, Lahore. A total of 111 patients, aged 40-60 years, of both genders undergoing uncomplicated phacoemulsification, were selected. Operative time was noted. After surgery, patients were shifted to post-surgical wards and were discharged from there. All patients were followed up in the OPD for 12 weeks. After 12 weeks, patients were examined again for central macular thickness on OCT, and if the thickness rose by>30% from baseline, then macular oedema was labelled.
Results: The age range in this study was from 40 to 60 years, with a mean age of 51.53 ± 4.34 years. The majority of the patients, i.e. 66 (49.46%), were between 51 to 60 years of age. Out of these 111 patients, 51 (45.95%) were male and 60 (54.05%) were female, with a male-to-female ratio of 1:1.2. Mean pre-therapy CMT was 211.40 ± 10.98 µm, and post-therapy was 237.48 ± 9.79 µm. Frequency of macular oedema after uncomplicated phacoemulsification was seen in 20 (18.02%) patients.
Conclusion: This study concluded that the frequency of macular oedema after uncomplicated phacoemulsification is quite high.
References
2. Jin G, Li Q, Hu D, Zeng Q. Changes In Retinal Thickness And Vessel Density After Phacoemulsification With OCTA In Cataract. 2022;In press.
3. El-Sayed El-Ymany Abo Karemh M, Ezzat Khallaf M, El-Din Abd El- Monem Ziada H. Effect of variable phaco times of constant phaco power on macular thickness. Al-Azhar Med J. 2021;50(1):491-500.
4. Mostafa Elewa ES, Metwally Bayoumy H, Samir Hamed Sherif A. Effect of uncomplicated phacoemulsification on intraocular pressure. Al-Azhar Med J. 2019;48(2):135-44.
5. Kim B-J, Ahn YJ, Oh H-Y, Choi SI, Yoo Y-S, Whang W-J, et al.Assessment for Macular Thickness after Uncomplicated Phacoemulsification Using Optical Coherence Tomography. Korea J Ophthalmol. 2022;36(4):296-305.
6. Stock RA, Galvan DK, Godoy R, Bonamigo EL. Comparison of macular thickness by optical coherence tomography measurements after uneventful phacoemulsification using ketorolac tromethamine, nepafenac, vs a control group, preoperatively and postoperatively. Clin Ophthalmol. 2018;12:607-11.
7. Giansanti F, Bitossi A, Giacomelli G, Virgili G, Pieretti G, Giuntoli M, et al. Evaluation of Macular Thickness after Uncomplicated Cataract Surgery using Optical Coherence Tomography. Eur J Ophthalmol. 2013;23(5):751-6.
8. Kazim NA, Hughes BA. Macular Thickness Before and After Cataract Surgery. Invest Ophthalmol Vis Sci. 2005;46(l3):766 -.
9. Gharbiya M, Cruciani F, Cuozzo G, Parisi F, Russo P, Abdolrahimzadeh S. Macular thickness changes evaluated with spectral domain optical coherence tomography after uncomplicated phacoemulsification. Eye. 2013;27(5):605-11.
10. Haroun HE, Saeed MAN, Thabet Labeb BH. Comparison in Macular Thickness between Non diabetic and Uncomplicated Diabetics after Uncomplicated Phacoemulsification. Egypt J Med Res. 2022;3(1):95-105.
11. Kim BJ, Ahn YJ, Oh HY, Choi SI, Yoo YS, Whang WJ, et al. Assessment for Macular Thickness after Uncomplicated Phacoemulsification Using Optical Coherence Tomography. Korea J Ophthalmol. 2022;36(4):296-305.
12. Markomichelakis NN, Halkiadakis I, Pantelia E, et al. Patterns of macular edema in patients with uveitis: qualitative and quantitative assessment using optical coherence tomography. Ophthalmology 2004;111:946-53.
13. Antcliff RJ, Stanford MR, Chauhan DS, et al. Comparison between optical coherence tomography and fundus fluorescein angiography for the detection of cystoid macular edema in patients with uveitis. Ophthalmology 2000; 107:593-9.
14. Otani T, Kishi S, Maruyama Y. Patterns of diabetic macular edema with optical coherence tomography. Am J Ophthalmol 1999;127:688 -93.
15. Hee MR, Puliafito CA, Wong C, et al. Quantitative assessment of macular edema with optical coherence tomography. Arch Ophthalmol 1995;113:1019-29.
16. Nussenblatt RB, Kaufman SC, Palestine AG, et al. Macular thickening and visual acuity. Measurement in patients with cystoid macular edema. Ophthalmology 1987;94:1134-9.
17. Ozdek SC, Erdinc MA, Gurelik G, et al. Optical coherence tomographic assessment of diabetic macular edema: comparison with fluorescein angiographic and clinical findings. Ophthalmologica 2005;219:86 -92
18. Nelson ML, Martidis A. Managing cystoid macular edema after cataract surgery. Curr Opin Ophthalmol 2003; 14:39–43.
19. Ray S, D'Amico DJ. Pseudophakic cystoid macular edema. Semin Ophthalmol 2002; 17:167–180.
20. Von Jagow B, Ohrloff C, Kohnen T. Macular thickness after uneventful cataract surgery determined by optical coherence tomography. Graefes Arch Clin Exp Ophthalmol 2007; 245:1765–1771.
21. Joussen AM, Poulaki V, Le ML, Koizumi K, Esser C, Janicki H, et al. A central role for inflammation in the pathogenesis of diabetic retinopathy. FASEB J 2004; 18:1450–1452.
22. Escaravage GK Jr, Cohen KL, Patel SB, Hartnett ME, Armstrong BD, Janowski CM. Quantification of macular and optic disc hyperfluorescence after phacoemulsification in diabetes mellitus. J Cataract Refract Surg 2006; 32:803–811.
23. Kim SJ, Equi R, Bressler NM. Analysis of macular edema after cataract surgery in patients with diabetes using optical coherence tomography. Ophthalmology 2007; 114:881–889.
24. Kim BY, Smith SD, Kaiser PK. Optical coherence tomographic patterns of diabetic macular edema. Am J Ophthalmol. 2006;142(3):405–412.
25. Oh JH, Chuck RS, Do JR, Park CY. Vitreous hyper reflective dots in optical coherence tomography and cystoid macular oedema after uneventful phacoemulsification surgery. PLoS One 2014; 9:e95066.
26. Dowler JGF, Sehmi KS, Hykin PG, Hamilton AMP. The natural history of macular edema cataract surgery in diabetes. Ophthalmology 1999; 106:663–668.
27. Belair ML, Kim SJ, Thorne JE, Dunn JP, Kedhar SR, Brown DM, Jobs DA. Incidence of cystoid macular edema after cataract surgery in patients with and without uveitis using optical coherence tomography. Am J Ophthalmol 2009; 148:128–135.
28. Funatsu H, Yamashita H, Ikeda T, Mimura T, Eguchi S, Hori S. Vitrous levels of interleukin-6 and vascular endothelial growth factor are related to diabetic macular edema. Ophthalmology. 2003; 110:1690–1696.
29. El-Sobkya HM, El-Sebaeya AR, El-Hagaab AA, Gaber NK. Evaluation of the progression of diabetic retinopathy after phacoemulsification. Menouf Med J 2014; 27:643–649.