CORRELATION OF CENTRAL MACULAR THICKNESS ON OCT FOLLOWING PANRETINAL PHOTOCOAGULATION WITH HBA1C AMONG DIABETIC PATIENTS
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Keywords
Proliferative diabetic retinopathy (PDR), Optical coherence tomography
Abstract
Background: PDR is defined as the formation of new retinal vessels due to poor glycemic control patients with diabetes mellitus .Among the risk factors, one of the most significant risk factor that predicts this complication is the long term hyperglycemia with the long duration of disease, that ultimately causes the development of advance diabetic eye disease .The definite treatment of PDR is via PRP laser , that reduce oxygen demand of retinal tissue and prevents further ischemic mediated damage.
Objective: Find out any change in the CMT and its correlation with HbA1c following PRP by OCT macula among patients with PDR.
Methods: This study was conducted at the department of Ophthalmology, Services Institute of Medical Sciences, Services Hospital Lahore, Pakistan. Study period was of six months from December 2023 to June 2024. This study included a total of fourty eyes from fourty patients with diagnosed proliferative diabetic retinopathy , study participants were divided into two groups, Group mA with HbA1c below 7.5% comprising of twenty patients , and group B comprising of twenty patients with HbA1c between 8.5 and 9.0%, both study groups were treated with pan retinal photocoagulation performed in single session with 1500 laser burn spots This laser treatment was followed by Optical coherence tomography , four weeks after the sessions. Central macular thickness was measured for a change before and after PRP laser sessions.
Results: In our study, patients had a mean age of 48.71±2.42 years, ,the measured mean baseline CMT before the PRP laser sessions was recorded at baseline thickness of 230.45±5.0 and four weeks after the PRP session ,the mean CMT value was 238.50±5.30 among patients in group A and 257±3.5 microns among group B patients. (p-value of 0.001)
Conclusion: There was no statistically proven significant change found in macular thickness before and after PRP session upto to four weeks of follow-up via OCT macula
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Muhammad Hamza Shahid
Senior Registrar Ophthalmology, Services Institute of Medical Sciences, Services Hospital, Lahore, Pakistan
Muhammad Mueen Bhatti
Ophthalmology Department, Lahore Medical & Dental College, Lahore, Pakistan
Tehmina Imdad
Assistant Professor Ophthalmology, Ghulam Muhammad Mahar Medical College, Sukkur, Pakistan
Muhammad Nasrullah Khan
Assistant Professor Ophthalmology, Services Institute of Medical Sciences, Services Hospital Lahore, Pakistan
Khawaja Mohsin Ihsan
Professor of Ophthalmology, Services Institute of Medical Sciences, Services Hospital, Lahore, Pakistan
Saqib Siddiq
Professor of Ophthalmology, Services Institute of Medical Sciences, Services Hospital, Lahore, Pakistan