THE FREQUENCY OF H. PYLORI INFECTION AMONG DYSPEPTIC PATIENTS PRESENTING AT TERTIARY CARE HOSPITALS OF QUETTA
Main Article Content
Keywords
helicobacter, Pylori, Infection, Dyspepsia, Frequency.
Abstract
Background: Helicobacter pylori (H. pylori) infection is the most common cause of bacterial infection worldwide infecting more than 50% of the world's population predominantly in the developing countries. H. pylori is an important risk factor for gastritis, peptic ulcers, and gastric cancer likely due to the extensive inflammation in the stomach.
Objectives: To determine the frequency of H. Pylori infection among dyspeptic patients presenting at tertiary care hospital.
Study Design: Descriptive, cross-sectional study.
Study duration: 14th March 2023 to 13th February 2024.
Settings: Department of Gastroenterology, Bolan Medical Complex Hospital Quetta.
Methods: A study was conducted involving patients presenting with gastrointestinal symptoms. Participants were stratified into age groups (18–40 years and 41–60 years), gender (male and female), and by duration of symptoms (≤6 months and >6 months). The presence of H. pylori infection was assessed using diagnostic tests, and statistical analysis was performed to evaluate associations, with a p-value < 0.05 considered significant.
Results: In the 18–40 age group, 54 individuals tested positive and 15 negative, while in the 41–60 group, 47 were positive and 7 negative (p = 0.208), indicating no significant association with age. Among males, 52 tested positive and 17 negative while among females, 49 were positive and 5 negative. A statistically significant difference was found between genders (p = 0.027). Regarding symptom duration, 70 tested positive with symptoms ≤6 months, and 31 with symptoms >6 months (p = 0.918), showing no significant relationship.
Conclusion: The study found a statistically significant association between H. pylori infection and gender, but not with age or duration of symptoms. Gender-specific factors may influence infection prevalence and warrant further investigation.
References
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Safia Sana
Bolan Medical Complex Hospital, Quetta, Balochistan, Pakistan
Gulmina Kasi
Peoples Medical Collage Hospital, Nawabshah Sindh, Pakistan
Shama Noreen
Bolan Medical Complex Hospital, Quetta, Balochistan, Pakistan
Muhammad Essa Khan
Bolan Medical Complex Hospital, Quetta, Balochistan, Pakistan
Iqra Badar
Peoples Medical Collage Hospital, Nawabshah Sindh, Pakistan
Muhammad Waseem
M. Islam Medical and Dental Collage, Gujranwala Punjab, Pakistan
Samreen Sana
Bolan Medical Collage, Quetta, Pakistan
Bahauddin
Bolan Medical Complex Hospital, Quetta, Balochistan, Pakistan
Abdul Qadir
Bolan Medical Complex Hospital, Quetta, Balochistan, Pakistan
Muhammad Kamran Taj
CASVAB University of Balochistan, Quetta, Pakistan