FACTORS LINKED TO EARLY DETECTION OF ORAL AND PHARYNGEAL CANCER
Main Article Content
Keywords
Pharyngeal cancer, oral cancer, early detection, risk factors, awareness, and delayed diagnosis, Pakistan.
Abstract
Introduction: Oral and pharyngeal cancers continue to rise in low and middle-income countries, which have a high proportion of patients presenting at advanced stages and poor survival. The ability to get early detection remains a significant factor in developing countries like Pakistan because of the low levels of knowledge and health facility accessibility.
Objective: To identify and evaluate the factors associated with early detection of oral and pharyngeal cancer among patients in Pakistan.
Materials and Method: The cross-sectional study was conducted at Oral and Maxillofacial Surgery Department, Foundation University Islamabad over six months from January 2024 to June 2024. A total of 150 newly diagnosed patients were included in this study. Demographic information, risk factors, knowledge and perceptions, and tumor profiles were obtained through communication and patient records.
Results: A disturbing discovery was made regarding the stage of diagnosis, where only 30% of the patients were diagnosed early. The results showed that people from higher education, those who reside in urban areas, or those who previously had awareness of the symptoms were likely to get it early. According to the results, most patients stated that they used tobacco and sought medical care after getting the symptoms.
References
2- Huang, J., Chan, S.C., Ko, S., Lok, V., Zhang, L., Lin, X., Lucero‐Prisno III, D.E., Xu, W., Zheng, Z.J., Elcarte, E. and Withers, M., 2023. Disease burden, risk factors, and trends of lip, oral cavity, pharyngeal cancers: A global analysis. Cancer medicine, 12(17), pp.18153-18164.
3- González-Ruiz, I., Ramos-García, P., Ruiz-Ávila, I. and González-Moles, M.Á., 2023. Early diagnosis of oral cancer: A complex polyhedral problem with a difficult solution. Cancers, 15(13), p.3270.
4- Da Cunha, A.R., Compton, K., Xu, R., Mishra, R., Drangsholt, M.T., Antunes, J.L.F., Kerr, A.R., Acheson, A.R., Lu, D., Wallace, L.E. and Kocarnik, J.M., 2023. The global, regional, and national burden of adult lip, oral, and pharyngeal cancer in 204 countries and territories: a systematic analysis for the global burden of disease study 2019. JAMA oncology, 9(10), pp.1401-1416.
5- Wierzbicka, M., Klussmann, J.P., San Giorgi, M.R., Wuerdemann, N. and Dikkers, F.G., 2021. Oral and laryngeal HPV infection: Incidence, prevalence and risk factors, with special regard to concurrent infection in head, neck and genitals. Vaccine, 39(17), pp.2344-2350.
6- Chaturvedi, A.K., Freedman, N.D. and Abnet, C.C., 2022. The evolving epidemiology of oral cavity and oropharyngeal cancers. Cancer Research, 82(16), pp.2821-2823.
7- Singla, A., Goel, A.K., Oberoi, S., Jain, S., Singh, D. and Kapoor, R., 2022. Impact of demographic factors on delayed presentation of oral cancers: A questionnaire-based cross-sectional study from a rural cancer center. Cancer Research, Statistics, and Treatment, 5(1), pp.45-51.
8- Barsouk, A., Aluru, J.S., Rawla, P., Saginala, K. and Barsouk, A., 2023. Epidemiology, risk factors, and prevention of head and neck squamous cell carcinoma. Medical Sciences, 11(2), p.42.
9- Tranby, E.P., Heaton, L.J., Tomar, S.L., Kelly, A.L., Fager, G.L., Backley, M. and Frantsve-Hawley, J., 2022. Oral cancer prevalence, mortality, and costs in medicaid and commercial insurance claims data. Cancer Epidemiology, Biomarkers & Prevention, 31(9), pp.1849-1857.
10- González-Moles, M.Á., Aguilar-Ruiz, M. and Ramos-García, P., 2022. Challenges in the early diagnosis of oral cancer, evidence gaps and strategies for improvement: a scoping review of systematic reviews. Cancers, 14(19), p.4967.
11- Igissin, N., Zatonskikh, V., Telmanova, Z., Tulebaev, R. and Moore, M., 2023. Laryngeal cancer: epidemiology, etiology, and prevention: a narrative review. Iranian journal of public health, 52(11), p.2248.
12- Aghiorghiesei, O., Zanoaga, O., Nutu, A., Braicu, C., Campian, R.S., Lucaciu, O. and Berindan Neagoe, I., 2022. The world of Oral cancer and its risk factors viewed from the aspect of MicroRNA expression patterns. Genes, 13(4), p.594.
13- Gormley, M., Creaney, G., Schache, A., Ingarfield, K. and Conway, D.I., 2022. Reviewing the epidemiology of head and neck cancer: definitions, trends and risk factors. British Dental Journal, 233(9), pp.780-786.
14- Zhou, X.H., Huang, Y., Yuan, C., Zheng, S.G., Zhang, J.G., Lv, X.M. and Zhang, J., 2022. A survey of the awareness and knowledge of oral cancer among residents in Beijing. BMC Oral Health, 22(1), p.367.
15- Gribb, J.P., Wheelock, J.H. and Park, E.S., 2023. Human papilloma virus (HPV) and the current state of oropharyngeal cancer prevention and treatment. Delaware Journal of Public Health, 9(1), p.26.