FREQUENCY OF PANCYTOPENIA IN CHILDREN PRESENTING WITH MALARIA
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Keywords
Frequency; Pancytopenia; Children; Malaria
Abstract
Background: Pancytopenia is a hematological disorder that is caused by a numbers of factors including infections.
Objective: The aim of this study was to find out the frequency of Pancytopenia in Children Presenting with Malaria.
Material and method: The present cross-sectional descriptive study was carried out at the Department of Pediatrics Gambat Institute of medical and health sciences for a period of six months from May 2016 to October 2016 after taking permission from the ethical board of the institute. A total of 240 children of various age group (6 months to 18 years) presented with fever, chills, and rigors tested positive for malaria were included. Patients with fever underwent investigations, including special smears and MP. Informed consent from parents was obtained. Data analysis was performed using SPSS version 24.
Results: In the current study a total of 240 malarial individuals were enrolled out of which 144(60%) were male and 96(40%) were females. A total of 93(38.7%) children had pancytopenia, whereas 147(61.25%) were not observed with Pancytopenia. Pancytopenia was more frequent in younger children. Pancytopenia was most prevalent in children with age below 5 years old 24 (36.3%), followed by age 6-10 years 49 (48.5%) and over 16 years old 7 (43.75%) participants. Pancytopenia was seen in 55 (38.1%) male and 34 (35.4%) female malaria patients.
Conclusion: The present study concluded that pancytopenia is associated with malaria and in this study its prevalence was 38.7%. Therefore early diagnosis and treatment of malaria is crucial for the prevention of pancytopenia.
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Arifa Jabeen
Assistant professor Pediatrics Gambat Institute of medical and health sciences
Amna Begum
FCPS, MBBS Obs and Gynae Assistant professor Pir Sayed Abdul Qadir Shah jilani institute of medical sciences Gambat
Asghar Ali Memon
Assistant professor at Pir Syed Abdul Qadir Shah jeelani institute of medical sciences Gambat