TOPICAL GELS FOR DRUG DELIVERY: RECENT ADVANCEMENTS IN FORMULATION AND FUTURE DIRECTIONS IN CLINICAL PRACTICE
Main Article Content
Keywords
Classification, Gel applications, gel formulation, limitations, pharmaceutical gels.
Abstract
The main intention behind this review is to provide updated information related to the recent developments in terms of novel topical preparations including the basic concepts of dermal drug delivery systems. Topical drug delivery systems especially gels have several advantages such as it provides prolonged application to the site of action ultimately improving the therapeutic effect. A gel is a semisolid combination of a three-dimensional matrix of cross-linked materials. The three dimensional matrix of gel is mainly composed of a gelling agent and water. This review highlights the fundamentals of gel formulation and the factors affecting, along with the classification, advantages, limitations, and applications of different types of pharmaceutical gels such as niosomal/proniosomal gel, emulgels, bigels, xerogels and aerogels, organogels and hydrogels.
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Sep 15, 2024
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How to Cite
Sadia Ahmed Zuberi, Fawaz Jaffar, Nousheen Alam, Samina Sheikh, Nimra Aamir, Hasnan Ali, & Rahat Fatima Naqvi. (2024). TOPICAL GELS FOR DRUG DELIVERY: RECENT ADVANCEMENTS IN FORMULATION AND FUTURE DIRECTIONS IN CLINICAL PRACTICE. Journal of Population Therapeutics and Clinical Pharmacology, 31(9), 3892-3910. https://doi.org/10.53555/avm14c73
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Author Biographies
Sadia Ahmed Zuberi
Faculty of Pharmaceutical Sciences, SBB Dewan University, Karachi, Pakistan
Fawaz Jaffar
Faculty of Pharmaceutical Sciences, SBB Dewan University, Karachi, Pakistan
Nousheen Alam
Faculty of Pharmaceutical Sciences, SBB Dewan University, Karachi, Pakistan
Samina Sheikh
Faculty of Pharmacy and Pharmaceutical Sciences, Ziauddin University, Karachi, Pakistan
Nimra Aamir
Faculty of Pharmaceutical Sciences, SBB Dewan University, Karachi, Pakistan
Hasnan Ali
Product Lead, Manufacturing Sciences and Technology, GlaxoSmithKline, Karachi, Pakistan
Rahat Fatima Naqvi
Faculty of Pharmacy, IBADAT International University, Islamabad
How to Cite
Sadia Ahmed Zuberi, Fawaz Jaffar, Nousheen Alam, Samina Sheikh, Nimra Aamir, Hasnan Ali, & Rahat Fatima Naqvi. (2024). TOPICAL GELS FOR DRUG DELIVERY: RECENT ADVANCEMENTS IN FORMULATION AND FUTURE DIRECTIONS IN CLINICAL PRACTICE. Journal of Population Therapeutics and Clinical Pharmacology, 31(9), 3892-3910. https://doi.org/10.53555/avm14c73