SEROPREVALENCE OF RUBELLA AMONG THE WOMEN (WITH BAD OBSTETRIC HISTORY) VISITING A TERTIARY CARE HOSPITAL LOCATED IN CENTRAL INDIA
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Keywords
Rubella, Bad Obsteric History, Seroprevalence, IgG, IgM
Abstract
Background: Rubella is a mild exanthematous disease of global distribution. However, there is a risk of infection to the foetus subsequently causing congenital defects, if it infects susceptible pregnant women. Aims & Objective: To detect seroprevalence of Rubella in women with Bad Obstetric History.
Materials & Method: The present prospective study was carried out from June 2018 to May 2019 in the Department of Microbiology of a teaching tertiary care hospital located in the Central India. The serum samples received from 107 women with Bad Obstetric History were tested for TORCH panel. Rubella IgG & IgM antibodies were tested by ELISA method (Calbiotech, USA).
Results & Discussion: Among the 55 serum samples showing Rubella seropositivity, 10.9 % samples were IgM positive, 80 % were IgG positive and 9.09 % samples were found to be positive for both IgM & IgG antibodies. Several studies have also quoted the seroprevalence of Rubella ranging from 4.0 % to 29 %. Conclusions: The results indicate high prevalence of Rubella among the female with Bad Obstetric History. Serological screening has contributed to the prevention of congenital infection due to Rubella and also helps in proper management of fetal outcomes.
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Chandra Pratap Singh Rathore
Microbiologist Department of Microbiology, District hospital Ratlam M.P
Dr Amit Kumar
Associate professor Department of Microbiology, Zydus Medical College Dahod Gujrat
Dr Trupti Bajpai
Assistant professor Department of Microbiology, Sri Aurobindo Medical College & PG Institute Indore M.P.
Dr Dipak Patanvadia
Assistant professor Department of Microbiology, Zydus Medical College Dahod Gujarat .
Dr Pankti Pargi
Assistant Professor, Department of Microbiology, Zydus Medical College Dahod Gujarat.
Dr Rekha Kishori
Associate Professor, Department of Microbiology, Zydus medical College Dahod Gujarat.