PREVALENCE OF MICROORGANISMS IN HIGH VAGINAL SWABS FROM WOMEN PRESENTING WITH VAGINAL DISCHARGE IN OUTPATIENT CLINICS
Main Article Content
Keywords
Vaginal discharge, bacterial vaginosis, Gardnerella vaginalis, Candida albicans, antimicrobial susceptibility, outpatient clinics
Abstract
Introduction: Consequently, the conclusions of this particular study corroborate the importance of performing microbiological analysis to recognize the root cause of the discharge. So, clinical signs and physical findings provide a clue to presumed pathogens, while clinical laboratory evaluation is essential for diagnostic confirmation of the etiologic agent. This is especially the case in clinical or diagnostic situations where patients display reinfections or chronic infections, and the microbial pathogen(s) responsible might not be apparent.
Objectives: To establish the prevalence and variety of microorganisms isolated in high vaginal swabs among women attending outpatient clinics with symptoms of vaginal discharge.
Materials and Methods: A cross-sectional study was performed at Department of Obstetrics & Gynaecology, Hayatabad Medical Complex Peshawar, Pakistan over a period of six months. The high vaginal swabs were then obtained from 200 nonpregnant, adult female attendees aged between 18-45 years with vaginal discharge. Culture and sensitivity were done in order to isolate and sensitively identify bacteria and their susceptibility to antimicrobial agents.
Results: Gardnerella vaginalis was the most frequently isolated pathogen, 32 %, with Candida albicans 25% and Escherichia coli 18%. Some of the other microorganisms included were Streptococcus species, Trichomonas vaginalis, and Neisseria gonorrhoeae.
Conclusion: Bacterial vaginosis and fungal infections are the common causes of vaginal discharge, as confirmed by microbiological examination.
References
2- Ramejo, B.B., Soomro, S., Sadaf, S., Sohu, K.M. and Ramejo, M.A., 2021. Frequency of common organisms causing vaginal discharge in sexually active women in reproductive age group. The Professional Medical Journal, 28(01), pp.86-89.
3- Baek, J.C., Jo, H.C., Lee, S.M., Park, J.E., Cho, I.A. and Sung, J.H., 2021. Prevalence of Pathogens and Other Microorganisms in Premenopausal and Postmenopausal Women with Vulvovaginal Symptoms: A Retrospective Study in a Single Institute in South Korea. Medicina, 57(6), p.577.
4- Sethi, S., Sharma, N., Sharma, M., Dadwal, R., Singh, C., Chaudhary, H., Malhotra, S., Yadav, R. and Gupta, V., 2022. Prevalence of nonviral reproductive tract infections/sexually transmitted infections in female patients with cervicovaginal discharge: Excerpts from a regional reference center in North India. Indian Journal of Sexually Transmitted Diseases and AIDS, 43(2), pp.135-140.
5- Hashem, H.E., Ibrahim, Z.H., Nada, A.M. and Ahmed, W.O., 2024. The Valuable Microbiological Role of Vaginal and Cervical Swabs in The Management of Persistent and Recurrent Reproductive Tract Infections (RTIs). Egyptian Journal of Hospital Medicine, 95.
6- Bibi, K., Nisar, M., Wadood, S., Kifayatullah, M., Nasir, S., Kamran, M. and Shakeeb, N., 2023. Magnitude of Bacterial Vaginosis in Non-Pregnant Outpatient Women Presenting Vaginal Discharge in Police Service Hospital Peshawar, Khyber Pakhtunkhwa, Pakistan. The Ethiopian Journal of Health Development, 37(2).
7- Khaskheli, M., Baloch, S., Baloch, A.S. and Shah, S.G.S., 2021. Vaginal discharge during pregnancy and associated adverse maternal and perinatal outcomes. Pakistan journal of medical sciences, 37(5), p.1302.
8- KIRAT, S. and ÇİFTÇİ, N., 2024. Evaluation of the Causative Microorganisms and Antibiogram Results in Women with Vaginal Swab Cultures Through Prediagnosis of Vaginitis. Journal of General Medicine/Genel Tıp Dergisi, 34(6).
9- Majigo, M.V., Kashindye, P. and Mtulo, Z., 2021. Bacterial vaginosis, the leading cause of genital discharge among women presenting with vaginal infection in Dar es Salaam, Tanzania. African health sciences, 21(2), pp.531-537.
10- Yasin, J., Ayalew, G., Dagnaw, M., Shiferaw, G. and Mekonnen, F., 2021. Vulvovaginitis prevalence among women in gondar, Northwest Ethiopia: Special emphasis on aerobic vaginitis causing bacterial profile, antimicrobial susceptibility pattern, and associated factors. Infection and Drug Resistance, pp.4567-4580.
11- Khadka, S., Khatri, R. and Chaudhary, R., 2024. Infective Vaginal Discharge among Women of the Reproductive Age in the Outpatient Department of a Primary Care Centre. JNMA: Journal of the Nepal Medical Association, 62(270), p.103.
12- Intra, J., Sala, M.R., Brambilla, P., Carcione, D. and Leoni, V., 2022. Prevalence and species distribution of microorganisms isolated among non-pregnant women affected by vulvovaginal candidiasis: A retrospective study over a 20 year-period. Journal of Medical Mycology, 32(3), p.101278.
13- Aboud, S., Buhalata, S.N., Onduru, O.G., Chiduo, M.G., Kwesigabo, G.P., Mshana, S.E., Manjurano, A.M., Temu, M.M., Kishamawe, C. and Changalucha, J.M., 2023. High prevalence of sexually transmitted and Reproductive Tract Infections (STI/RTIs) among patients attending STI/Outpatient Department clinics in Tanzania. Tropical Medicine and Infectious Disease, 8(1), p.62.
14- Yalew, G.T., Muthupandian, S., Hagos, K., Negash, L., Venkatraman, G., Hagos, Y.M., Meles, H.N., Weldehaweriat, H.H., Al-Dahmoshi, H.O. and Saki, M., 2022. Prevalence of bacterial vaginosis and aerobic vaginitis and their associated risk factors among pregnant women from northern Ethiopia: A cross-sectional study. PloS one, 17(2), p.e0262692.
15- Idowu, M.O., Makinde, G.I., Oluranti, O.O., Adebayo, M.A. and Adekunle, O.A., 2022. Prevalence of vulvo-vaginal candidiasis among women attending clinics in selected Hospitals in Oyo State, Southwest, Nigeria. Journal of Public Health and Epidemiology, 14(1), pp.45-52.