ANESTHESIA-RELATED COMPLICATIONS IN PATIENTS WITH COMORBID RESPIRATORY CONDITIONS

Main Article Content

Aisha Alyassi
Meera Al Shamsi
Zain Ul Abidin
Asma Mohamed
Meera Ahmed
Meera Alharmoodi
Nabaa Shakir Mahmood
Fatma Almadani
Roda Alshamsi
Randa A. Harbi
Madhovarshinii Rajesh

Keywords

anesthesia, respiratory conditions, COPD, anesthesia complications, perioperative management, comorbidities.

Abstract

Background: Anesthesia in patients with chronic respiratory conditions such as chronic obstructive pulmonary disease (COPD) presents unique challenges and risks. The prevalence of these conditions necessitates a thorough understanding of anesthesia-related complications in this population (1, 2).


Objectives: This review aims to evaluate the incidence of anesthesia-related complications in patients with comorbid respiratory conditions and to identify strategies for optimizing anesthesia management in these patients.


Methodology: A comprehensive literature search was conducted using databases such as PubMed, Cochrane Library, and Google Scholar to identify relevant studies published from 1990 to 2024. Articles were selected based on their focus on anesthesia outcomes in patients with respiratory comorbidities, including COPD and asthma. Studies were analyzed for complications related to anesthesia, management protocols, and outcomes (3, 4).


Results: The findings indicate that patients with comorbid respiratory conditions experience higher rates of anesthesia-related complications, including respiratory failure, prolonged ventilation, and increased postoperative morbidity (5, 6). Notably, the management of such patients requires tailored approaches, including preoperative assessments, optimized perioperative care, and careful selection of anesthetic agents to mitigate risks (7, 8).


Conclusion: Anesthesia in patients with comorbid respiratory conditions is associated with significant risks that require comprehensive preoperative evaluation and individualized management strategies. Enhanced awareness and adherence to guidelines can improve outcomes and minimize complications in this vulnerable population (9, 10).


 

Abstract 208 | pdf Downloads 80

References

1. Albert, R. K., Connett, J., Bailey, W. C., et al. (2011). Azithromycin for prevention of exacerbations of COPD. New England Journal of Medicine, 365(8), 689-698. https://doi.org/10.1056/NEJMoa1104623
2. Anthonisen, N. R., Manfreda, J., Warren, C. P., et al. (1987). Antibiotic therapy in exacerbations of chronic obstructive pulmonary disease. Annals of Internal Medicine, 106(2), 196-204. https://doi.org/10.7326/0003-4819-106-2-196
3. Changizi, M., & Rio, K. (2010). Harnessing color vision for visual oximetry in central cyanosis. Medical Hypotheses, 74(1), 87-91. https://doi.org/10.1016/j.mehy.2009.07.047
4. Celli, B. R., Cote, C. G., Marin, J. M., et al. (2004). The body-mass index, airflow obstruction, dyspnea, and exercise capacity index in chronic obstructive pulmonary disease. New England Journal of Medicine, 350(10), 1005-1012. https://doi.org/10.1056/NEJMoa023191
5. Decramer, M., Janssens, W., & Miravitlles, M. (2012). Chronic obstructive pulmonary disease. The Lancet, 379(9823), 1341-1351. https://doi.org/10.1016/S0140-6736(11)60968-9
6. GBD 2015 Chronic Respiratory Disease Collaborators. (2017). Global, regional, and national deaths, prevalence, disability-adjusted life years, and years lived with disability for chronic obstructive pulmonary disease and asthma, 1990-2015: A systematic analysis for the Global Burden of Disease Study 2015. Lancet Respiratory Medicine, 5(9), 691-706. https://doi.org/10.1016/S2213-2600(17)30293-X
7. Lumb, A., & Biercamp, C. (2014). Chronic obstructive pulmonary disease and anaesthesia. Continuing Education in Anaesthesia Critical Care & Pain, 14(1), 1-7. https://doi.org/10.1093/bjaceaccp/mkt023
8. Mattos, W. L., Signori, L. G., Borges, F. K., et al. (2009). Accuracy of clinical examination findings in the diagnosis of COPD. Jornal Brasileiro de Pneumologia, 35(5), 404-408. https://doi.org/10.1590/s1806-37132009000500005
9. McCarthy, B., Casey, D., Devane, D., et al. (2015). Pulmonary rehabilitation for chronic obstructive pulmonary disease. Cochrane Database of Systematic Reviews, 2015(2), CD003793. https://doi.org/10.1002/14651858.CD003793.pub3
10. Melani, A. S. (2015). Long-acting muscarinic antagonists in chronic obstructive pulmonary disease. Expert Review of Clinical Pharmacology, 8(4), 479-501. https://doi.org/10.1586/17512433.2015.1047742
11. Nannini, L. J., Lasserson, T. J., & Poole, P. (2012). Combined corticosteroid and long-acting beta2-agonist in one inhaler versus long-acting beta2-agonists for chronic obstructive pulmonary disease. Cochrane Database of Systematic Reviews, 2012(9), CD006829. https://doi.org/10.1002/14651858.CD006829.pub3
12. Parker, C. M., Voduc, N., Aaron, S. D., & O'Donnell, D. E. (2005). Physiological changes during symptom recovery from moderate exacerbations of COPD. European Respiratory Journal, 26(3), 420-428. https://doi.org/10.1183/09031936.05.00139604
13. Qaseem, A., Wilt, T. J., Weinberger, S. E., et al. (2011). Diagnosis and management of stable chronic obstructive pulmonary disease: A clinical practice guideline update from the American College of Physicians, American College of Chest Physicians, American Thoracic Society, and European Respiratory Society. Annals of Internal Medicine, 155(3), 179-191. https://doi.org/10.7326/0003-4819-155-3-201108020-00008
14. Rabe, K. F., Fabbri, L. M., Kristiansen, S., et al. (2009). Roflumilast in symptomatic chronic obstructive pulmonary disease: Two randomized clinical trials. Lancet, 374(9691), 685-694. https://doi.org/10.1016/S0140-6736(09)61255-1
15. Rabe, K. F., Watz, H., & Kristiansen, S. (2011). Update on roflumilast, a phosphodiesterase 4 inhibitor for the treatment of chronic obstructive pulmonary disease. British Journal of Pharmacology, 163(1), 53-67. https://doi.org/10.1111/j.1476-5381.2011.01232.x
16. Shaker, S. B., Dirksen, A., Bach, K. S., & Mortensen, J. (2007). Imaging in chronic obstructive pulmonary disease. COPD: Journal of Chronic Obstructive Pulmonary Disease, 4(2), 143-161. https://doi.org/10.1080/15412550701246838
17. Singh, D., Agusti, A., Anzueto, A., et al. (2019). Global Strategy for the Diagnosis, Management, and Prevention of Chronic Obstructive Lung Disease: The GOLD Science Committee Report 2019. European Respiratory Journal, 53(5). https://doi.org/10.1183/13993003.00164-2019
18. Stockley, R. A. (1999). Neutrophils and protease/antiprotease imbalance. American Journal of Respiratory and Critical Care Medicine, 160(5 Pt 2), S49-S52. https://doi.org/10.1164/ajrccm.160.supplement
19. Tanoue, L. T., Tanner, N. T., Gould, M. K., & Silvestri, G. A. (2015). Lung cancer screening. American Journal of Respiratory and Critical Care Medicine, 191(1), 19-33. https://doi.org/10.1164/rccm.201410-1777PP
20. ZuWallack, R. L., Mahler, D. A., & Reilly, D. (2001). Salmeterol plus theophylline combination therapy in the treatment of COPD. Chest, 119(6), 1661-1670. https://doi.org/10.1378/chest.119.6.1661

Most read articles by the same author(s)