ANALYSIS OF POST-OPERATIVE PAIN IN ROOT CANAL THERAPY USING CALCIUM HYDROXIDE (CA(OH)₂)-BASED SEALER
Main Article Content
Keywords
Analgesic consumption, Calcium hydroxide-based sealers, Healing outcomes, Post-operative pain, Root canal therapy
Abstract
Background: Post-operative pain is a common concern in root canal therapy (RCT), affecting patient comfort and treatment outcomes. Calcium hydroxide (Ca(OH)₂)-based sealers are hypothesized to provide better pain relief and healing due to their anti-inflammatory and antimicrobial properties.
Objective: To evaluate the impact of Ca(OH)₂-based sealers on post-operative pain, analgesic consumption, and healing outcomes compared to non-Ca(OH)₂-based sealers in RCT.
Study Design & Setting: This experimental study was conducted at Sharif Medical & Dental College, Lahore over six months from Jan 2023 to June 2023.
Methodology: A total of 150 patients were randomly allocated into two groups: an experimental group using Ca(OH)₂-based sealers and a control group using non-Ca(OH)₂-based sealers. Standardized RCT procedures were performed, and post-operative pain was assessed using a visual analog scale (VAS) at 6, 24, 48, and 72 hours. Analgesic consumption and healing outcomes were also recorded. Statistical analysis was performed using SPSS version 25.0, with p < 0.05 considered significant.
Results: The experimental group demonstrated significantly lower pain scores at all-time points (p < 0.001). Analgesic consumption was reduced in the experimental group, with 24% requiring pain relief compared to 51% in the control group (p < 0.001). Complete healing was observed in 90.7% of the experimental group compared to 74.7% of the control group (p = 0.01).
Conclusion: Ca(OH)₂-based sealers significantly reduce post-operative pain, lower analgesic requirements, and enhance healing outcomes, making them an effective choice for improving RCT success.
References
2. Gulabivala K, Ng YL. Factors that affect the outcomes of root canal treatment and retreatment—A reframing of the principles. International Endodontic Journal. 2023 Mar;56:82-115.
3. Wenzler JS, Falk W, Frankenberger R, Braun A. Temporary Root Canal Obturation with a Calcium Hydroxide-Based Dressing: A Randomized Controlled Clinical Trial. Antibiotics. 2023 Nov 26;12(12):1663.
4. Fransson H, Dawson V. Tooth survival after endodontic treatment. International Endodontic Journal. 2023;56:140-53.
5. Zou X, Zheng X, Liang Y, Zhang C, Fan B, Liang J, Ling J, Bian Z, Yu Q, Hou B, Chen Z. Expert consensus on irrigation and intracanal medication in root canal therapy. International Journal of Oral Science. 2024;16(1):23.
6. Huang D, Wang X, Liang J, Ling J, Bian Z, Yu Q, Hou B, Chen X, Li J, Ye L, Cheng L. Expert consensus on difficulty assessment of endodontic therapy. International Journal of Oral Science. 2024 1;16(1):22.
7. Graunaite I, Skucaite N, Lodiene G, Agentiene I, Machiulskiene V. Effect of resin-based and bioceramic root canal sealers on postoperative pain: a split-mouth randomized controlled trial. Journal of Endodontics. 2018 May 1;44(5):689-93.
8. Zamparini F, Lenzi J, Duncan HF, Spinelli A, Gandolfi MG, Prati C. The efficacy of premixed bioceramic sealers versus standard sealers on root canal treatment outcome, extrusion rate and post‐obturation pain: A systematic review and meta‐analysis. International Endodontic Journal. 2024 Apr 12.
9. Paz A, Vasconcelos I, Ginjeira A. Evaluation of postoperative pain after using bioceramic materials as endodontic sealers. EC Dent. Sci. 2018;17:1739-48.
10. Wong J, Cheung GS, Lee AH, McGrath C, Neelakantan P. PROMs following Root Canal Treatment and Surgical Endodontic Treatment. International dental journal. 2023 Feb 1;73(1):28-41.
11. Chalub LO, Nunes GP, Ferrisse TM, Strazzi-Sahyon HB, Dos Santos PH, Gomes-Filho JE, Cintra LT, Sivieri-Araujo G. Postoperative pain in root canal treatment with ultrasonic versus conventional irrigation: a systematic review and meta-analysis of randomized controlled trials. Clinical oral investigations. 2022 Apr;26(4):3343-56.
12. Nagendrababu V, Gutmann JL. Factors associated with postobturation pain following single-visit nonsurgical root canal treatment: A systematic review. Quintessence International. 2017 Mar 1;48(3).
13. Ujjan S, Saeed N, Soomro SP, Manzoor F, Malhi P, Iqbal Z. Evaluation of Post-operative Pain by using Calcium Hydroxide Based Root Canal Sealer: A Clinical Study. Journal of Pharmaceutical Research International. 2021;33(42A):397–401.
14. Anjaneyulu K, Nivedhitha MS. Influence of calcium hydroxide on the post-treatment pain in Endodontics: A systematic review. Journal of Conservative Dentistry and Endodontics. 2014 May 1;17(3):200-7.
15. Büker M, Sümbüllü M, Ali A, Ünal O, Arslan H. The Effects of Calcium Silicate-and Calcium Hydroxide–based Root Canal Sealers on Postoperative Pain: A Randomized Clinical Trial. Journal of Endodontics. 2023 Dec 1;49(12):1588-94.
16. Moraes VG, Meyfarth SR, Maranón-Vásquez GA, Antunes LA, Antunes LS. Influence of root canal sealer composition on postoperative pain after endodontic treatment of permanent teeth: a systematic review and meta-analyses. Brazilian Dental Science. 2024 May 17;27(1).
17. Ferreira ND, Gollo EK, Boscato N, Arias A, Silva EJ. Postoperative pain after root canal filling with different endodontic sealers: a randomized clinical trial. Brazilian Oral Research. 2020 Jul 15;34:e069.
18. Shahroz N, Surti S, Irha Hussain Zaidi MA, Sajjad S, Noor Z. The Effect of Two Different Root Canal Sealers on Post Obturation Pain. Pakistan Journal of Medical & Health Sciences. 2023 Apr 21;17(03):344-48.
19. Thakur D, Makkar S, Aggarwal A, Mushtaq F, Mushtaq U. Comparative evaluation of post-operative pain with different calcium hydroxide formulations when used as intracanal medicament in root canal treatment-In vivo study. IP Indian J Conserv Endod. 2020;5:100-4.
20. Monteiro CM, Martins AC, Reis A, de Geus JL. Effect of endodontic sealer on postoperative pain: a network meta-analysis. Restorative Dentistry & Endodontics. 2023 Feb;48(1).