THYROID DYSFUNCTION AMONG HYPERTENSIVE PREGNANT WOMEN IN TERTIARY CARE HOSPITAL

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Tahir Zaman Khan
Maria iqbal
Amir jalal
Shaista Ghumro
Iqra Lodhi
Madiha Iqbal
Rida Haider

Keywords

Thyroid Dysfunction, Hypertensive, Pregnant Women

Abstract

Background: About 10% of pregnant women are affected by Hypertension which is a universal health problem that leads to hospitalization, and even death of the mother. These illnesses of gestation period may by characterized by deferent syndromes, comprising long-lasting and gestational hypertension that results in seizures.


Aim: The Aim of this study was to find out the Thyroid Dysfunction among Hypertensive Pregnant Women in tertiary care hospital


Material and Methods: This observational study was conducted at Hayatabad Medical Complex from august 2019 to July 2023 after the approval from the ethical committee of the institute. A total of 101 pregnant women visited the hospital were included. The inclusion criteria was pregnant women diagnosed with hypertension and thyroid dysfunction and patients who discharge,  pass away,  or  leave  the  hospital  in  between  period of the study were excluded. Data were collected base on various variables like parameters like age, gestational age, length of stay were assessed using one sample t-test and were analyzed through SPSS software version 24 to find the outcomes. For Test of significance of hypertension and hypothyroidism in pregnant women we used Pearson Chi-square test {χ2 -test}


Results A total of 101 patients participated in this study which were recognized and examined for final outcome. Among these patients the frequency of hypothyroidism was (47%)  followed by hypertension  (32%) and females  with  both  hypertension and hypothyroidism were 21% as presented in SPSS software version 24 which was used for the Statistical analysis and parameters were evaluated through one sample t-test. The p value found was <0.001 which indicates  that these parameters are statistically significant. So in pregnant women there was statistically noteworthy variance among the high blood pressure and hypothyroidism.


Conclusion:  It was identified from this study that there were changes in the thyroid function of pregnant women with hypertension and hypertensive pregnant women had hypothyroidism.


 

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References

1. Fabry, I.G.; Richart, T.; Cheng, X.; Van Bortel, L.M.; Staessen, J.A. Diagnosis and treatment of hypertensive disorders during pregnancy. Acta Clin. Belg. 2010, 65, 229–23619
2. World Health Organization. International society of hypertension guidelines for the management of hypertension (Guideline subcommittee). J. Hypertens 1999, 11, 151–183.
3. Braunthal, S.; Brateanu, A. Hypertension in pregnancy: Pathophysiology and treatment. SAGE Open Med. 2019, 7, 2050312119843700.
4. Alavi, A.; Adabi, K.; Nekuie, S.; Jahromi, E.K.; Solati, M.; Sobhani, A. Thyroid Dysfunction and autoantibodies association with hypertensive disorders during pregnancy. J. Pregn. 2012, 3, 742695
5. Singh, A.; Singh, S. Status of thyroid hormone parameters in hypertensive disorders of pregnancy. Nepal. Med. J. 2020, 3, 302–305
6. Saki, F.; Dabbaghmanesh, M.H.; Ghaemi, S.Z. Thyroid function in pregnancy and its influences on maternal and fetal outcomes. Int. J. Endocrinol. Metab. 2014, 12, e19378.
7. Ramtainal, R.; Dhanoo, A. Subclinical hypothyroidism causing hypertension in pregnancy. J. Am. Soc. Hypertens. 2016, 10, 691–693
8. Han y, wang j, wang x, Ouyang l, li y. Relationship between subclinical hypothyroidism in pregnancy and hypertensive disorder of pregnancy: A systematic review and meta-analysis. Frontiers in endocrinology. 2022;13
9. Singh A, Singh S. Status Of Thyroid Hormone Parameters In Hypertensive Disorders Of Pregnancy. Nepalese Medical Journal. 2020;3(1):302-5
10. Wilson KL, casey BM, mcintire DD, halvorson LM, cunningham FG. Subclinical thyroid disease and the incidence of hypertension in pregnancy. Obstetrics & gynecology. 2012;119(2, part 1):315 20
11. Singh V, Srivastava M. Associated risk factors with pregnancyinduced hypertension: A hospital-based KAP study. International journal of medicine and public health. 2015;5(1):59
12. Saraladevi R, Nirmalakumari T, Shreen B, Usha rani V. Prevalence of thyroid disorder in pregnancy and pregnancy outcome. IAIM, 2016; 3(3): 1-11.
13. Singh A, Singh S. Status Of Thyroid Hormone Parameters In Hypertensive Disorders Of Pregnancy. Nepalese Medical Journal. 2020;3(1):302-5
14. Kumari R, Kumari A, Roopam S, Tirkey R. Correlation of thyroid status with severity of hypertension in pregnancy. International journal of health and clinical research 2020;35:254-98
15. Kashi Z, Bahar A, Akha O, Hassanzade S, Esmaeilisaraji L, Hamzehgardeshi Z. Levothyroxine dosage requirement during pregnancy in well-controlled hypothyroid women: A longitudinal study. Global journal of health science. 2015;8(4):227

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