IDENTIFICATION OF SIGNIFICANT CHEMICAL AND BIOACTIVE MARKERS OF SESBANIA SESBAN (L.) MERR. SEED OIL BY PHYTOCHEMICAL AND PHYSICOCHEMICAL ANALYSIS
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Keywords
Seed oil, Bioactive, GC-MS, Antioxidant, Iodine Value, Fatty Acids, Phytochemical, Physicochemical.
Abstract
Chemical and physicochemical characterization of Sesbania sesban seed oil was carried out. Oil was subjected to chemical analysis by GC-FID and GC-MS. Saturated and unsaturated fatty acids were identified Palmitic acid was found in (57.24%), Stearic acid (22.8 %) eicosanoic acid (4.5 %) and linoleic acid (4.4%). Thirteen (13) compounds belonging to diverse class were identified. Presence of 2-methylbutanal, 2-amylfuran, Pentanoic acid, Hexanoic acid, Decanal, Eucalyptol, Vitamin-D, Palmitic acid, Oleic acid, Plant steroids and Alpha Pinene were detected. This justified the use of oil as folk medicine. These constituents collectively are responsible for Antimicrobial, anti- inflammatory, analgesic, antidepressant, anti-anxiolytic, anti-parkinsonian, anti-glaucoma, muscle relaxant, antihypertensive, diuretic, anti-ulcer, anti-ageing, and anticancer activities of this extremely important medicinal oil. Iodine value was found 10.730 for Sesbania sesban oil while SAP value was found 366.207 with total fat 51.220 %, saturated (47.055%) and unsaturated (4.163%). Antioxidant activity was also done of oil from seed by DPPH assay and found insignificant. Further research is required to determine the specific dose and safety profile of recommended dose for given medical condition.
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Ijaz Ali
Department of Pharmacognosy, Faculty of Pharmaceutical sciences, Government College University Faisalabad, Punjab Pakistan.
Abdul Haq Khan
Department of Pharmaceutical Chemistry, Faculty of Pharmaceutical Sciences, Government College University Faisalabad, Punjab Pakistan.
Awais Ali Zaidi
Department of Pharmacy, The University of Chenab Pakistan.
Wahid Shafiq
Department of Pharmacy, The University of Chenab Pakistan.
Muhammad Umar Khayam Sahibzada
Department of Pharmacy, The Sahara University Narowal, Punjab Pakistan.
Kainat Ilyas
Department of Pharmaceutical Chemistry, Faculty of Pharmaceutical Sciences, Government College University Faisalabad, Punjab Pakistan.
Abdul Saboor
Department of Pharmaceutical Chemistry, Faculty of Pharmaceutical Sciences, Government College University Faisalabad, Punjab Pakistan.
Hajra Iqbal
Department of Pharmaceutical Chemistry, Faculty of Pharmaceutical Sciences, Government College University Faisalabad, Punjab Pakistan.
Muhammad Amtiaz Aslam
Department of Pharmaceutical Chemistry, Faculty of Pharmaceutical Sciences, Government College University Faisalabad, Punjab Pakistan.
Muhammad Basit Mujahid
Department of Pharmacy, University of Lahore, Lahore, Punjab Pakistan.