FREQUENCY OF CRP LEVELS IN PATIENTS PRESENTING WITH ACUTE CORONARY SYNDROME
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Keywords
Acute Coronary Syndrome, C-reactive protein, inflammation, cardiovascular risk, Pakistan, risk stratification
Abstract
Methods: This observational cohort study conducted at Lady Reading Hospital Peshawar, Pakistan in the duration from January, 2024 to June, 2024 included 246 adult ACS patients. Patients were confirmed by clinical presentation, ECG changes, and elevated cardiac biomarkers. Exclusions included chronic inflammatory conditions, recent major surgery, trauma, or known malignancies. CRP levels were measured using a high-sensitivity assay. Statistical analysis was performed using SPSS version 26.0, with descriptive statistics summarizing baseline characteristics and chi-square tests for categorical variables and ANOVA or Kruskal-Wallis tests for continuous variables.
Results: Mean CRP level was 9.8 mg/L (SD: 7.4) with a median of 8.5 mg/L. Elevated CRP levels (>10 mg/L) were found in 52.8% of patients. No significant differences in CRP levels were observed concerning age, gender, BMI, hypertension, diabetes, and smoking status.
Conclusion: A high prevalence of elevated CRP levels in ACS patients highlights the role of inflammation in ACS. Routine CRP measurement may enhance risk stratification and management.
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