Clinical Pharmacogenomic of Vildagliptin in Egyptian Patients with Insulin Resistance

Main Article Content

Hamdy Abdelaal Badry Ahmed, Randa Mohamed Talaat, Manal Osama El- Hamshary, Nermin Reda Tayel, and Mona Abd Elmotaleb A. Hussein

Keywords

obesity, GLP1R gene, vildagliptin, insulin resistant

Abstract

Background: Pharmacogenomics is the study of how genes affect a person’s response to drugs. Insulin resistance is a pathological state in which a given insulin concentration produces a less-than-expected biological effect.
Aim: This study aimed to investigate the association of rs6923761 variants in GLP 1R gene response to vildagliptin after 6 months’ follow-up in Egyptian patients with insulin resistance (IR).

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