RELATIONSHIP BETWEEN DIABETES AND TEMPOROMANDIBULAR JOINT DISORDER
Main Article Content
Keywords
Diabetes, Temporomandibular Joint, Osteoarthritis, Physical Symptoms, RDC/TMD
Abstract
Background: The inflammatory reaction brought on by diabetes, which can make TMJ symptoms worse, is what distinguishes the association between diabetes and temporomandibular disorders (TMD). Diabetes-related side effects, including elevated inflammation and diabetic neuropathy, can exacerbate TMD and impair temporomandibular joint (TMJ) function.
Methods: The following experiment can be used to examine the connection between diabetes and temporomandibular disorders (TMD). Get a sample of people with and without TMD symptoms, including those who are diabetic and those who are not. To diagnose TMD, do thorough dental and medical tests that include measurements of joint sounds, jaw mobility, and pain thresholds. Gather blood samples so that inflammatory indicators including interleukin-6 (IL-6) and C-reactive protein (CRP) may be measured. Give thorough surveys to evaluate people's quality of life, diabetes control techniques, and the intensity of their TMD symptoms. Employ statistical methods to assess the frequency and intensity of TMD in groups with and without diabetes, and establish a relationship between the levels of inflammatory markers and TMD symptoms.
Results: Such an investigation might show that, in comparison to non-diabetic controls, diabetes patients had higher prevalence and more severe TMD symptoms. Increased TMD symptoms in diabetic individuals may be strongly correlated with elevated levels of inflammatory markers (IL-6, CRP), indicating that systemic inflammation related to diabetes exacerbates TMD. These results would be consistent with the theory that diabetes has a role in the onset and severity of temporomandibular problems.
Conclusion: The study showed a clear correlation between temporomandibular disorders' increasing incidence and severity and diabetes mellitus.Elevated inflammatory markers in diabetic patients suggest that systemic inflammation plays a key role in exacerbating TMD symptoms. These findings highlight the importance of integrated care approaches that address diabetes management and TMD treatment to improve patient outcomes.
References
2. Amin R, Bahu TK, Widmer B, Dalton RN, and Dunger DB examine the longitudinal relationship between limited joint mobility, height, insulin-like growth factor 1 levels, and the risk of developing microalbuminuria in the Oxford Regional Prospective Study (Arch Dis Child. 2005;90(10):1039–44).
3. Mineoka Y, Ishii M, Hashimoto Y, Hata S, Tominaga H, Nakamura N, et al. find that limited joint mobility of the hand correlates with incident hospitalization due to infection in patients with type 2 diabetes (Diabetes Res Clin Pract. 2020;161:108049).
4. Gokcen N, Cetinkaya Altuntas S, Coskun Benlidayi I, Sert M, Nazlican E, and Sarpel T identify diabetic cheiroarthropathy as an overlooked rheumatologic manifestation of diabetes (Clin Rheumatol. 2019;38(3):927–32).
5. Fatemi A, Iraj B, Barzanian J, Maracy M, and Smiley A compare musculoskeletal manifestations in diabetic versus prediabetic patients (Int J Rheum Dis. 2015;18(7):791–9).
6. Rosenbloom AL describes the discovery, description, and decline of limited joint mobility in childhood diabetes (J Clin Endocrinol Metab. 2013;98(2):466–73).
7. Collin HL, Niskanen L, Uusitupa M, Töyry J, Collin P, Koivisto AM, et al. focus on oral symptoms and signs in elderly patients with type 2 diabetes mellitus, emphasizing diabetic neuropathy (Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2000;90(3):299–305).
8. Uemura M, Toda I, Kawashima W, Yoshimoto G, Fang YR, Xu YJ, et al. conduct a morphological study of the articular disc and capillary of the retrodiscal tissue in a type 2 spontaneous diabetes mellitus rat model (Okajimas Folia Anat Jpn. 2015;92(3–4):53–9).
9. Oles RD links glucose intolerance with temporomandibular joint pain-dysfunction syndrome (Oral Surg Oral Med Oral Pathol. 1977;43(4):546–53).
10. Neyzi O, Bundak R, Gokcay G, Gunoz H, Furman A, Darendeliler F, and Bas F provide reference values for weight, height, head circumference, and body mass index in Turkish children (J Clin Res Pediatr Endocrinol. 2015;7(4):280-293).
11. Demir K, Konakci E, Ozkaya G, Kasap Demir B, Ozen S, Aydin M, and Darendeliler F introduce new features for child metrics, including further growth references and blood pressure calculations (J Clin Res Pediatr Endocrinol. 2020;12(2):125-129).
12. Edel E, Carlsson J, and Stener-Victorin E examine health-related quality of life in child patients with temporomandibular disorder pain in the European Journal of Pain (2007;11(5):557–63)
13. Johnson EL, Feldman H, Butts A, Chamberlain J, Collins B, and Doyle-Delgado K, along with their colleagues, provide the standards of medical care in diabetes—2020 abridged for primary care providers in Clinical Diabetes (2020).
14. Barbosa TS, Leme MS, Castelo PM, and Gavião MB evaluate oral health-related quality of life measures for children and preadolescents with temporomandibular disorder in Health Quality Life Outcomes (2011;9:32;38(1):10–38).
15. De Santis TO, Motta LJ, Biasotto-Gonzalez DA, and others conduct an accuracy study of the main screening tools for temporomandibular disorder in children and adolescents, published in the Journal of Bodywork and Movement Therapies (2014;18(1):87-91).
Article Sidebar
Article Details
This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.
All articles published in JPTCP are licensed under Copyright Creative Commons Attribution-NonCommercial 4.0 International License.
Dr Ayesha Ahmed
Fauji Foundation Hospital, Multan
Dr Saadia Hayee Shaikh
BDS, RDS, CHPE, Demonstrator DME, Fazaia Medical College, Islamabad
Hrishik Iqbal
Department of Mathematics and Natural Sciences, BRAC University, Dhaka, Bangladesh.
Dr Ravi Shanker Essarani
Bachelor of Dental Surgery, Ziauddin College of Dentistry, Karachi, Sindh, Pakistan
Dr. Hafiz Mahmood Azam
B.D. S M.Phil. C.H.P. E Associate Professor, Head of Department, Science of Dental Materials, Muhammed Medical and Dental College, Mirpurkhas
Dr Mahwish Ashraf
MBBS, Medical Officer, POF Hospital, Wah Cantt