PLATELET RICH PLASMA FOR PERIPHERAL NERVE REGENERATION. A SYSTEMATIC REVIEW
Main Article Content
Keywords
peripheral nerve, entrapment, regeneration, platelet-rich plasma, dextrose
Abstract
Background
Platelet-rich plasma (PRP) injections have recently been marketed as a form of autologous cell therapy under the banner of regenerative medicine despite limited scientific evidence on its use for treating peripheral nerve lesions (ED).
Aim
To evaluate the evidence on PRP treatment for nerve lesions and determine the current trends in provision of this treatment.
Methods
A critical review of the literature on PRP using the MEDLINE, EMBASE, COCHRANE, PUBMED databases.
Outcomes
This systematic review focuses on the clinical use of, regulation of, and evidence for PRP in the treatment of peripheral nerve lesion.
Results
There are a huge number of published peer-reviewed articles demonstrating clinical outcomes pertaining to the use of PRP for nerve lesions in human. The technique and clinical application for PRP is currently patented, with a global total of 71different research studies and literature findings positive used of PRP for nerve lesions.
Conclusion
Despite a global presence of PRP clinics and ongoing active marketing and public interest in regenerative medicine, no scientific evidence has been published to establish an evidence-based risk-benefit profile for PRP use for ED in humans.
References
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This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.
All articles published in JPTCP are licensed under Copyright Creative Commons Attribution-NonCommercial 4.0 International License.
Ahmed Hassan Usman
Junior Registrar Trauma & Orthopaedics at University Hospital, Birmingham
Talha Khalid
Senior House Officer, Paediatric Neurosurgery Department, The Children's Hospital, Lahore
Muzammil Iqbal
SHO, Plastic Surgery Department, Shaikh Zayed Hospital, Lahore
Mustabshir Hussain
SHO, Cardiology Department, Shaikh Zayed Hospital, Lahore
Hassan Raza
Medical Officer, Gujranwala Medical College and Teaching Hospital, Gujranwala
Sania Maqbool
Lecturer, Department of Physical Therapy, Lahore College for Women University LCWU, Lahore